Increase in Ocular Syphilis Cases at Ophthalmologic Reference Center, France, 2012–2015

We describe the frequency, demographic and clinical features, and visual outcomes of ocular syphilis infections observed during 2012–2015 at a tertiary reference center in Paris, France. Twenty-one cases (29 eyes) were identified. The occurrence of ocular syphilis increased from 1 case in 2012 to 5...

Descripción completa

Detalles Bibliográficos
Autores principales: Pratas, Ana Catarina, Goldschmidt, Pablo, Lebeaux, David, Aguilar, Claire, Ermak, Natalia, Benesty, Jonathan, Charlier, Caroline, Benveniste, Edgar, Merabet, Lilia, Sedira, Neila, Hope-Rapp, Emilie, Chaumeil, Christine, Bodaghi, Bahram, Héron, Emmanuel, Sahel, José-Alain, Lortholary, Olivier, Errera, Marie-Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Synopsis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782877/
https://www.ncbi.nlm.nih.gov/pubmed/29350138
http://dx.doi.org/10.3201/eid2402.171167
Descripción
Sumario:We describe the frequency, demographic and clinical features, and visual outcomes of ocular syphilis infections observed during 2012–2015 at a tertiary reference center in Paris, France. Twenty-one cases (29 eyes) were identified. The occurrence of ocular syphilis increased from 1 case in 2012 to 5 cases in 2013, 6 cases in 2014, and 9 cases in 2015 (2.22–25.21/1,000 individual patients/year for the period). Among case-patients, an annual 20%–33% were co-infected with HIV. Seventy-six percent of ocular syphilis infections occurred in men who have sex with men. Seventy-five percent of case-patients had a good final visual outcome (best-corrected visual acuity >0.3 logMAR score). Visual outcome was worse for HIV-positive patients than for HIV-negative patients (p = 0.0139). At follow-up, the best visual outcomes were observed in patients whose mean time from first ocular symptom to consultation was 15 days (SD +19 days).

Ejemplares similares