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The role of brigatinib in crizotinib-resistant non-small cell lung cancer

Despite the advances in new targeted therapies in ALK positive population, most patients progress under ALK inhibitors within first 2 years; being the brain the most frequent site of relapse. ALK mutations, in ~30% of patients, are the main known mechanism of resistance. Classically, second-generati...

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Detalles Bibliográficos
Autores principales:	Mezquita, Laura, Planchard, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783011/ https://www.ncbi.nlm.nih.gov/pubmed/29403310 http://dx.doi.org/10.2147/CMAR.S129963

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