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Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome
BACKGROUND: Polycystic ovary syndrome (PCOS), as the most common endocrine disorder among reproductive-aged women may lead to psychological morbidity. OBJECTIVES: The present study set out to evaluate the severity of depression in PCOS and non-PCOS women and to evaluate correlation between depressio...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Electronic physician
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783134/ https://www.ncbi.nlm.nih.gov/pubmed/29403625 http://dx.doi.org/10.19082/5820 |
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author | Enjezab, Behnaz Eftekhar, Maryam Ghadiri-Anari, Akram |
author_facet | Enjezab, Behnaz Eftekhar, Maryam Ghadiri-Anari, Akram |
author_sort | Enjezab, Behnaz |
collection | PubMed |
description | BACKGROUND: Polycystic ovary syndrome (PCOS), as the most common endocrine disorder among reproductive-aged women may lead to psychological morbidity. OBJECTIVES: The present study set out to evaluate the severity of depression in PCOS and non-PCOS women and to evaluate correlation between depression score with body mass index, HOMA-IR, and testosterone level in every group (PCOS and non-PCOS women) in Yazd province. METHODS: In this cross-sectional study, 62 women with PCOS and 61 non- PCOS subjects (20 to 40 years) who were attending Imam-Ali Clinic in Yazd, Iran from September 2014 through March 2015 participated. These persons completed the Beck Depression Short Inventory (BDI-S) Questionnaire. Frequency of depression in PCOD and healthy persons and correlation between depression severity with body mass index, HOMA-IR, testosterone level in PCOS and non- PCOS women were evaluated by ANOVA test and independent-samples t-test and Pearson correlation. P-value of less than 0.05 was considered as statistically significant. Data analyses were performed using SPSS version 16. RESULTS: Of 62 PCOS subjects, 40 (64.5%) were verified positive for depression, determined by the BDI-S Questionnaire. In the control group, 60.7% had depression. Mean±SE score of depression for PCOS and non-PCOS women were 7.47±5.54 and 7.57±5.77 respectively. There was no statistically significant correlation between body mass index, HOMA-IR, testosterone level with depression score in either group separately or together. CONCLUSIONS: We found considerable amounts of depression in our population. There is no correlation between body mass index, HOMA-IR, and testosterone level with depression score in our study. |
format | Online Article Text |
id | pubmed-5783134 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Electronic physician |
record_format | MEDLINE/PubMed |
spelling | pubmed-57831342018-02-05 Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome Enjezab, Behnaz Eftekhar, Maryam Ghadiri-Anari, Akram Electron Physician Original Article BACKGROUND: Polycystic ovary syndrome (PCOS), as the most common endocrine disorder among reproductive-aged women may lead to psychological morbidity. OBJECTIVES: The present study set out to evaluate the severity of depression in PCOS and non-PCOS women and to evaluate correlation between depression score with body mass index, HOMA-IR, and testosterone level in every group (PCOS and non-PCOS women) in Yazd province. METHODS: In this cross-sectional study, 62 women with PCOS and 61 non- PCOS subjects (20 to 40 years) who were attending Imam-Ali Clinic in Yazd, Iran from September 2014 through March 2015 participated. These persons completed the Beck Depression Short Inventory (BDI-S) Questionnaire. Frequency of depression in PCOD and healthy persons and correlation between depression severity with body mass index, HOMA-IR, testosterone level in PCOS and non- PCOS women were evaluated by ANOVA test and independent-samples t-test and Pearson correlation. P-value of less than 0.05 was considered as statistically significant. Data analyses were performed using SPSS version 16. RESULTS: Of 62 PCOS subjects, 40 (64.5%) were verified positive for depression, determined by the BDI-S Questionnaire. In the control group, 60.7% had depression. Mean±SE score of depression for PCOS and non-PCOS women were 7.47±5.54 and 7.57±5.77 respectively. There was no statistically significant correlation between body mass index, HOMA-IR, testosterone level with depression score in either group separately or together. CONCLUSIONS: We found considerable amounts of depression in our population. There is no correlation between body mass index, HOMA-IR, and testosterone level with depression score in our study. Electronic physician 2017-11-25 /pmc/articles/PMC5783134/ /pubmed/29403625 http://dx.doi.org/10.19082/5820 Text en © 2017 The Authors This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (http://creativecommons.org/licenses/by-nc-nd/3.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Original Article Enjezab, Behnaz Eftekhar, Maryam Ghadiri-Anari, Akram Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome |
title | Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome |
title_full | Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome |
title_fullStr | Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome |
title_full_unstemmed | Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome |
title_short | Association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome |
title_sort | association between severity of depression and clinico-biochemical markers of polycystic ovary syndrome |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783134/ https://www.ncbi.nlm.nih.gov/pubmed/29403625 http://dx.doi.org/10.19082/5820 |
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