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BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells

Chromatin remodeling is a key requirement for transcriptional control of cellular differentiation. However, the factors that alter chromatin architecture in mammary stem cells (MaSCs) are poorly understood. Here, we show that BPTF, the largest subunit of the NURF chromatin remodeling complex, is ess...

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Detalles Bibliográficos
Autores principales:	Frey, Wesley D., Chaudhry, Anisha, Slepicka, Priscila F., Ouellette, Adam M., Kirberger, Steven E., Pomerantz, William C.K., Hannon, Gregory J., dos Santos, Camila O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783326/ https://www.ncbi.nlm.nih.gov/pubmed/28579392 http://dx.doi.org/10.1016/j.stemcr.2017.04.031

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