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A Distinct Class of Genome Rearrangements Driven by Heterologous Recombination
Erroneous DNA repair by heterologous recombination (Ht-REC) is a potential threat to genome stability, but evidence supporting its prevalence is lacking. Here we demonstrate that recombination is possible between heterologous sequences and that it is a source of chromosomal alterations in mitotic an...
Autores principales: | León-Ortiz, Ana María, Panier, Stephanie, Sarek, Grzegorz, Vannier, Jean-Baptiste, Patel, Harshil, Campbell, Peter J., Boulton, Simon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783719/ https://www.ncbi.nlm.nih.gov/pubmed/29351848 http://dx.doi.org/10.1016/j.molcel.2017.12.014 |
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