The Negative Influence of Adiposity Extends to Intraindividual Variability in Cognitive Control among Preadolescent Children

OBJECTIVE: To investigate the relationship between adiposity and cognition using mean accuracy, mean reaction time, and intraindividual variability (IIV) among preadolescents. METHODS: Children 7–9 years old (N=233, 133 females) underwent dual-energy x-ray absorptiometry and a VO(2)peak test to assess whole-body adiposity and aerobic fitness relative to fat-free mass (VO(2)FF), respectively. Attentional inhibition was assessed using a modified flanker task. IIV was assessed as standard deviation (SDRT) and coefficient of variation (CVRT) of response time. Hierarchical linear regression analyses were performed to examine the relationships between adiposity and cognitive measures following adjustment of significant demographic factors, intelligence quotient, and VO(2)FF. RESULTS: Whole-body adiposity was negatively related to congruent trial mean accuracy and reaction time and to CVRT in both the congruent and incongruent trials. Differences in cognitive function across weight status were selectively evident for measures of IIV such that children with overweight/obesity (≥85(th) BMI-for-age percentile) exhibited higher CVRT for both the congruent and incongruent trials. CONCLUSION: This work provides additional evidence linking childhood obesity to poorer cognitive function and includes novel data extending the negative influence of adiposity to measures of intraindividual response variability in cognitive control, even after accounting for intellectual abilities, aerobic fitness and demographic factors.