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Applications of nanoparticle systems in drug delivery technology
The development of nanoparticle-based drug formulations has yielded the opportunities to address and treat challenging diseases. Nanoparticles vary in size but are generally ranging from 100 to 500 nm. Through the manipulation of size, surface characteristics and material used, the nanoparticles can...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783816/ https://www.ncbi.nlm.nih.gov/pubmed/29379334 http://dx.doi.org/10.1016/j.jsps.2017.10.012 |
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author | Rizvi, Syed A.A. Saleh, Ayman M. |
author_facet | Rizvi, Syed A.A. Saleh, Ayman M. |
author_sort | Rizvi, Syed A.A. |
collection | PubMed |
description | The development of nanoparticle-based drug formulations has yielded the opportunities to address and treat challenging diseases. Nanoparticles vary in size but are generally ranging from 100 to 500 nm. Through the manipulation of size, surface characteristics and material used, the nanoparticles can be developed into smart systems, encasing therapeutic and imaging agents as well as bearing stealth property. Further, these systems can deliver drug to specific tissues and provide controlled release therapy. This targeted and sustained drug delivery decreases the drug related toxicity and increase patient’s compliance with less frequent dosing. Nanotechnology has proven beneficial in the treatment of cancer, AIDS and many other disease, also providing advancement in diagnostic testing. |
format | Online Article Text |
id | pubmed-5783816 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-57838162018-01-29 Applications of nanoparticle systems in drug delivery technology Rizvi, Syed A.A. Saleh, Ayman M. Saudi Pharm J Article The development of nanoparticle-based drug formulations has yielded the opportunities to address and treat challenging diseases. Nanoparticles vary in size but are generally ranging from 100 to 500 nm. Through the manipulation of size, surface characteristics and material used, the nanoparticles can be developed into smart systems, encasing therapeutic and imaging agents as well as bearing stealth property. Further, these systems can deliver drug to specific tissues and provide controlled release therapy. This targeted and sustained drug delivery decreases the drug related toxicity and increase patient’s compliance with less frequent dosing. Nanotechnology has proven beneficial in the treatment of cancer, AIDS and many other disease, also providing advancement in diagnostic testing. Elsevier 2018-01 2017-10-25 /pmc/articles/PMC5783816/ /pubmed/29379334 http://dx.doi.org/10.1016/j.jsps.2017.10.012 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Rizvi, Syed A.A. Saleh, Ayman M. Applications of nanoparticle systems in drug delivery technology |
title | Applications of nanoparticle systems in drug delivery technology |
title_full | Applications of nanoparticle systems in drug delivery technology |
title_fullStr | Applications of nanoparticle systems in drug delivery technology |
title_full_unstemmed | Applications of nanoparticle systems in drug delivery technology |
title_short | Applications of nanoparticle systems in drug delivery technology |
title_sort | applications of nanoparticle systems in drug delivery technology |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783816/ https://www.ncbi.nlm.nih.gov/pubmed/29379334 http://dx.doi.org/10.1016/j.jsps.2017.10.012 |
work_keys_str_mv | AT rizvisyedaa applicationsofnanoparticlesystemsindrugdeliverytechnology AT salehaymanm applicationsofnanoparticlesystemsindrugdeliverytechnology |