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Association between satisfaction with and adherence to warfarin therapy on the control of international normalized ratio: A hospital-based study in Saudi Arabia

BACKGROUND: High satisfaction with, and adherence to, warfarin therapy are linked to better international normalized ratio (INR) control and good therapeutic outcomes. OBJECTIVE: This study was conducted to identify the association between satisfaction with, and adherence to, warfarin therapy and th...

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Autores principales: Balkhi, Balkhi, Al-Rasheedi, Mabrouk, Elbur, Abuabker Ibrahim, Alghamadi, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783818/
https://www.ncbi.nlm.nih.gov/pubmed/29379347
http://dx.doi.org/10.1016/j.jsps.2017.11.010
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author Balkhi, Balkhi
Al-Rasheedi, Mabrouk
Elbur, Abuabker Ibrahim
Alghamadi, Ahmad
author_facet Balkhi, Balkhi
Al-Rasheedi, Mabrouk
Elbur, Abuabker Ibrahim
Alghamadi, Ahmad
author_sort Balkhi, Balkhi
collection PubMed
description BACKGROUND: High satisfaction with, and adherence to, warfarin therapy are linked to better international normalized ratio (INR) control and good therapeutic outcomes. OBJECTIVE: This study was conducted to identify the association between satisfaction with, and adherence to, warfarin therapy and the control of the INR within the target therapeutic range. METHODS: A cross-sectional study was conducted from June 1 to August 31, 2016, at the Anticoagulation Clinic in the Cardiology Center at King Fahad Hospital, Qassim, Saudi Arabia. All adult patients included in the study were 18-years-old or older and were on warfarin therapy for 6 months or more. The data were collected through face-to-face interviews using a structured questionnaire. RESULTS: A total of 298 patients were included. Of them, 194 patients (65.1%) were males and 152 (51.0%) were classified as satisfied with their warfarin therapy. Secondary educational level and above (P = .001) and being non-Saudi (P = .026) were identified as determinants of a high level of satisfaction. Ninety-five (31.8%) participants were classified as adherent to the therapy, and satisfaction with treatment was the only predictor of adherence (P = .009). One hundred thirty-six patients (45.6%) achieved their target INR range. Satisfaction (P = .038) and adherence (P = .023) were significantly associated with better INR control. CONCLUSION: Substantial efforts are needed to improve patient satisfaction and adherence to treatment through different strategies in order to achieve the target therapeutic goal for warfarin treatment.
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spelling pubmed-57838182018-01-29 Association between satisfaction with and adherence to warfarin therapy on the control of international normalized ratio: A hospital-based study in Saudi Arabia Balkhi, Balkhi Al-Rasheedi, Mabrouk Elbur, Abuabker Ibrahim Alghamadi, Ahmad Saudi Pharm J Article BACKGROUND: High satisfaction with, and adherence to, warfarin therapy are linked to better international normalized ratio (INR) control and good therapeutic outcomes. OBJECTIVE: This study was conducted to identify the association between satisfaction with, and adherence to, warfarin therapy and the control of the INR within the target therapeutic range. METHODS: A cross-sectional study was conducted from June 1 to August 31, 2016, at the Anticoagulation Clinic in the Cardiology Center at King Fahad Hospital, Qassim, Saudi Arabia. All adult patients included in the study were 18-years-old or older and were on warfarin therapy for 6 months or more. The data were collected through face-to-face interviews using a structured questionnaire. RESULTS: A total of 298 patients were included. Of them, 194 patients (65.1%) were males and 152 (51.0%) were classified as satisfied with their warfarin therapy. Secondary educational level and above (P = .001) and being non-Saudi (P = .026) were identified as determinants of a high level of satisfaction. Ninety-five (31.8%) participants were classified as adherent to the therapy, and satisfaction with treatment was the only predictor of adherence (P = .009). One hundred thirty-six patients (45.6%) achieved their target INR range. Satisfaction (P = .038) and adherence (P = .023) were significantly associated with better INR control. CONCLUSION: Substantial efforts are needed to improve patient satisfaction and adherence to treatment through different strategies in order to achieve the target therapeutic goal for warfarin treatment. Elsevier 2018-01 2017-11-28 /pmc/articles/PMC5783818/ /pubmed/29379347 http://dx.doi.org/10.1016/j.jsps.2017.11.010 Text en © 2017 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Balkhi, Balkhi
Al-Rasheedi, Mabrouk
Elbur, Abuabker Ibrahim
Alghamadi, Ahmad
Association between satisfaction with and adherence to warfarin therapy on the control of international normalized ratio: A hospital-based study in Saudi Arabia
title Association between satisfaction with and adherence to warfarin therapy on the control of international normalized ratio: A hospital-based study in Saudi Arabia
title_full Association between satisfaction with and adherence to warfarin therapy on the control of international normalized ratio: A hospital-based study in Saudi Arabia
title_fullStr Association between satisfaction with and adherence to warfarin therapy on the control of international normalized ratio: A hospital-based study in Saudi Arabia
title_full_unstemmed Association between satisfaction with and adherence to warfarin therapy on the control of international normalized ratio: A hospital-based study in Saudi Arabia
title_short Association between satisfaction with and adherence to warfarin therapy on the control of international normalized ratio: A hospital-based study in Saudi Arabia
title_sort association between satisfaction with and adherence to warfarin therapy on the control of international normalized ratio: a hospital-based study in saudi arabia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783818/
https://www.ncbi.nlm.nih.gov/pubmed/29379347
http://dx.doi.org/10.1016/j.jsps.2017.11.010
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