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Role of PI3K in myocardial ischaemic preconditioning: mapping pro‐survival cascades at the trigger phase and at reperfusion

The Reperfusion Injury Salvage Kinase (RISK) pathway is considered the main pro‐survival kinase cascade mediating the ischaemic preconditioning (IPC) cardioprotective effect. To assess the role of PI3K‐Akt, its negative regulator PTEN and other pro‐survival proteins such as ERK and STAT3 in the cont...

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Detalles Bibliográficos
Autores principales:	Rossello, Xavier, Riquelme, Jaime A, Davidson, Sean M, Yellon, Derek M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783840/ https://www.ncbi.nlm.nih.gov/pubmed/29159980 http://dx.doi.org/10.1111/jcmm.13394

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