Cargando…

Neuroprotection by quercetin via mitochondrial function adaptation in traumatic brain injury: PGC‐1α pathway as a potential mechanism

The aim of this study was to investigate the neuroprotective effects of quercetin in mouse models of traumatic brain injury (TBI) and the potential role of the PGC‐1α pathway in putative neuroprotection. Wild‐type mice were randomly assigned to four groups: the sham group, the TBI group, the TBI+veh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xiang, Wang, Handong, Wen, Guodao, Li, Liwen, Gao, Yongyue, Zhuang, Zong, Zhou, Mengliang, Mao, Lei, Fan, Youwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783850/ https://www.ncbi.nlm.nih.gov/pubmed/29205806 http://dx.doi.org/10.1111/jcmm.13313

Ejemplares similares

Protective Effects of Quercetin on Mitochondrial Biogenesis in Experimental Traumatic Brain Injury via the Nrf2 Signaling Pathway
por: Li, Xiang, et al.
Publicado: (2016)

Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways
por: Zhang, Li, et al.
Publicado: (2017)

SS-31 Provides Neuroprotection by Reversing Mitochondrial Dysfunction after Traumatic Brain Injury
por: Zhu, Yihao, et al.
Publicado: (2018)

Sinomenine Provides Neuroprotection in Model of Traumatic Brain Injury via the Nrf2–ARE Pathway
por: Yang, Youqing, et al.
Publicado: (2016)

Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo
por: Li, Junyang, et al.
Publicado: (2016)

Quercetin and Quercetin-Rich Red Onion Extract Alter Pgc-1α Promoter Methylation and Splice Variant Expression
por: Devarshi, Prasad P., et al.
Publicado: (2017)

Quercetin Protects Ethanol-Induced Hepatocyte Pyroptosis via Scavenging Mitochondrial ROS and Promoting PGC-1α-Regulated Mitochondrial Homeostasis in L02 Cells
por: Zhao, Xingtao, et al.
Publicado: (2022)

Quercetin Attenuates Diabetic Peripheral Neuropathy by Correcting Mitochondrial Abnormality via Activation of AMPK/PGC-1α Pathway in vivo and in vitro
por: Zhang, Qian, et al.
Publicado: (2021)

Baicalin provides neuroprotection in traumatic brain injury mice model through Akt/Nrf2 pathway
por: Fang, Jiang, et al.
Publicado: (2018)

Interplay between VEGF and Nrf2 regulates angiogenesis due to intracranial venous hypertension
por: Li, Liwen, et al.
Publicado: (2016)

The Role of PGC-1α and Mitochondrial Biogenesis in Kidney Diseases
por: Fontecha-Barriuso, Miguel, et al.
Publicado: (2020)

PGC-1α activity and mitochondrial dysfunction in preterm infants
por: Mohammadi, Atefeh, et al.
Publicado: (2022)

Activation of the ATF2/CREB-PGC-1α pathway by metformin leads to dopaminergic neuroprotection
por: Kang, Hojin, et al.
Publicado: (2017)

Neuroprotective Effects of Quercetin on Ischemic Stroke: A Literature Review
por: Zhang, Leilei, et al.
Publicado: (2022)

Dynamic regulation of PGC-1α localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response
por: Anderson, Rozalyn M, et al.
Publicado: (2008)

Compensatory Increases in Nuclear PGC1α Protein Are Primarily Associated With Subsarcolemmal Mitochondrial Adaptations in ZDF Rats
por: Holloway, Graham P., et al.
Publicado: (2010)

Neuroprotective Effects of Quercetin in Alzheimer’s Disease
por: Khan, Haroon, et al.
Publicado: (2019)

Role of PGC-1α in the Mitochondrial NAD(+) Pool in Metabolic Diseases
por: Koh, Jin-Ho, et al.
Publicado: (2021)

Dietary Quercetin Supplementation in Mice Increases Skeletal Muscle PGC1α Expression, Improves Mitochondrial Function and Attenuates Insulin Resistance in a Time-Specific Manner
por: Henagan, Tara M., et al.
Publicado: (2014)

The Neuroprotective Effect of Tetramethylpyrazine Against Contusive Spinal Cord Injury by Activating PGC-1α in Rats
por: Hu, Jianzhong, et al.
Publicado: (2015)

Quercetin Reprograms Immunometabolism of Macrophages via the SIRT1/PGC-1α Signaling Pathway to Ameliorate Lipopolysaccharide-Induced Oxidative Damage
por: Peng, Jing, et al.
Publicado: (2023)

PGC-1α-Dependent Mitochondrial Adaptation Is Necessary to Sustain IL-2-Induced Activities in Human NK Cells
por: Miranda, Dante, et al.
Publicado: (2016)

Neuroprotective Effect of Oridonin on Traumatic Brain Injury via Inhibiting NLRP3 Inflammasome in Experimental Mice
por: Yan, Chaolong, et al.
Publicado: (2020)

PGC-1α induced mitochondrial biogenesis in stromal cells underpins mitochondrial transfer to melanoma
por: Kumar, Prakrit R., et al.
Publicado: (2022)

Neuroprotective effects of quercetin in diabetic rat retina
por: Ola, Mohammad S., et al.
Publicado: (2017)

Neuroprotective Effects of Quercetin in Pediatric Neurological Diseases
por: Alvarez-Arellano, Lourdes, et al.
Publicado: (2020)

PGC-1α-Mediated Mitochondrial Quality Control: Molecular Mechanisms and Implications for Heart Failure
por: Chen, Lei, et al.
Publicado: (2022)

PGC-1α is Dispensable for Exercise-Induced Mitochondrial Biogenesis in Skeletal Muscle
por: Rowe, Glenn C., et al.
Publicado: (2012)

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation to promote metastasis
por: LeBleu, Valerie S., et al.
Publicado: (2014)

PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity
por: Dabrowska, Aleksandra, et al.
Publicado: (2015)

HDL Mimetics Enhances Mitochondrial Function via Stimulation of PGC1-α
por: Zhang, Hang, et al.
Publicado: (2023)

PGC-1α and exercise intensity dependent adaptations in mouse skeletal muscle
por: Brandt, Nina, et al.
Publicado: (2017)

Apolipoprotein E regulates mitochondrial function through the PGC-1α-sirtuin 3 pathway
por: Yin, Junxiang, et al.
Publicado: (2019)

Inhibition of Cathepsin S Produces Neuroprotective Effects after Traumatic Brain Injury in Mice
por: Xu, Jianguo, et al.
Publicado: (2013)

Role of SIRT1/PGC-1α in mitochondrial oxidative stress in autistic spectrum disorder
por: Bu, Xiaosong, et al.
Publicado: (2017)

Korean Red Ginseng Improves Astrocytic Mitochondrial Function by Upregulating HO-1-Mediated AMPKα–PGC-1α–ERRα Circuit after Traumatic Brain Injury
por: Kim, Minsu, et al.
Publicado: (2021)

SIRT1 facilitates hepatocellular carcinoma metastasis by promoting PGC-1α-mediated mitochondrial biogenesis
por: Li, Yuming, et al.
Publicado: (2016)

Roles of Oxidative Stress, Apoptosis, PGC-1α and Mitochondrial Biogenesis in Cerebral Ischemia
por: Chen, Shang-Der, et al.
Publicado: (2011)

Erratum: PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity
por: Dabrowska, Aleksandra, et al.
Publicado: (2015)

Erratum: PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity
por: Dabrowska, Aleksandra, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_svs3qkucnt90939bf5quf48hgl