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Endogenous hormone 2‐methoxyestradiol suppresses venous hypertension‐induced angiogenesis through up‐ and down‐regulating p53 and id‐1

Brain arteriovenous malformations (AVMs) which associate with angiogenesis due to local hypertension, chronic cerebral ischaemia and tissue hypoxia usually lead to haemorrhage, however, the therapeutic medicine for the disease is still lacking. 2‐methoxyestradiol (2‐ME) has been shown effective in t...

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Detalles Bibliográficos
Autores principales:	Zou, Xiang, Zhang, Li, Yuan, Jie, Yang, Chunjie, Wu, Zehan, Song, Jianping, Zhu, Wei, Mao, Ying, Chen, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783857/ https://www.ncbi.nlm.nih.gov/pubmed/29193609 http://dx.doi.org/10.1111/jcmm.13399

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