Acute inhibition of PMCA4, but not global ablation, reduces blood pressure and arterial contractility via a nNOS‐dependent mechanism

Cardiovascular disease is the world's leading cause of morbidity and mortality, with high blood pressure (BP) contributing to increased severity and number of adverse outcomes. Plasma membrane calcium ATPase 4 (PMCA4) has been previously shown to modulate systemic BP. However, published data ar...

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Detalles Bibliográficos
Autores principales: Lewis, Sophronia, Little, Robert, Baudoin, Florence, Prehar, Sukhpal, Neyses, Ludwig, Cartwright, Elizabeth J., Austin, Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783868/
https://www.ncbi.nlm.nih.gov/pubmed/29193716
http://dx.doi.org/10.1111/jcmm.13371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783868/
https://www.ncbi.nlm.nih.gov/pubmed/29193716
http://dx.doi.org/10.1111/jcmm.13371

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