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Acute inhibition of PMCA4, but not global ablation, reduces blood pressure and arterial contractility via a nNOS‐dependent mechanism
Cardiovascular disease is the world's leading cause of morbidity and mortality, with high blood pressure (BP) contributing to increased severity and number of adverse outcomes. Plasma membrane calcium ATPase 4 (PMCA4) has been previously shown to modulate systemic BP. However, published data ar...
Autores principales: | Lewis, Sophronia, Little, Robert, Baudoin, Florence, Prehar, Sukhpal, Neyses, Ludwig, Cartwright, Elizabeth J., Austin, Clare |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783868/ https://www.ncbi.nlm.nih.gov/pubmed/29193716 http://dx.doi.org/10.1111/jcmm.13371 |
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