Cargando…

Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses

Current influenza vaccines provide limited protection against circulating influenza A viruses. A universal influenza vaccine will eliminate the intrinsic limitations of the seasonal flu vaccines. Here we report methodology to generate double-layered protein nanoparticles as a universal influenza vac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Lei, Mohan, Teena, Chang, Timothy Z., Gonzalez, Gilbert X., Wang, Ye, Kwon, Young-Man, Kang, Sang-Moo, Compans, Richard W., Champion, Julie A., Wang, Bao-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783933/ https://www.ncbi.nlm.nih.gov/pubmed/29367723 http://dx.doi.org/10.1038/s41467-017-02725-4

Ejemplares similares

Intranasal vaccination with influenza HA/GO-PEI nanoparticles provides immune protection against homo- and heterologous strains
por: Dong, Chunhong, et al.
Publicado: (2021)

Sequential immunizations with a panel of HIV-1 Env virus-like particles coach immune system to make broadly neutralizing antibodies
por: Mohan, Teena, et al.
Publicado: (2018)

Chimeric virus-like particles containing influenza HA antigen and GPI-CCL28 induce long-lasting mucosal immunity against H3N2 viruses
por: Mohan, Teena, et al.
Publicado: (2017)

Sequential Immunizations with heterosubtypic virus-like particles elicit cross protection against divergent influenza A viruses in mice
por: Luo, Yuan, et al.
Publicado: (2018)

Influenza Virus-Like Particles Containing M2 Induce Broadly Cross Protective Immunity
por: Song, Jae-Min, et al.
Publicado: (2011)

SARS‐CoV‐2 Spike Stem Protein Nanoparticles Elicited Broad ADCC and Robust Neutralization against Variants in Mice
por: Ma, Yao, et al.
Publicado: (2022)

Antiviral Activity of Fermented Ginseng Extracts against a Broad Range of Influenza Viruses
por: Wang, Ye, et al.
Publicado: (2018)

Intranasal Immunization with Influenza VLPs Incorporating Membrane-Anchored Flagellin Induces Strong Heterosubtypic Protection
por: Wang, Bao-Zhong, et al.
Publicado: (2010)

Quadrivalent influenza nanoparticle vaccines induce broad protection
por: Boyoglu-Barnum, Seyhan, et al.
Publicado: (2021)

Universal Influenza Vaccines, a Dream to Be Realized Soon
por: Zhang, Han, et al.
Publicado: (2014)

cGAMP-adjuvanted multivalent influenza mRNA vaccines induce broadly protective immunity through cutaneous vaccination in mice
por: Zhu, Wandi, et al.
Publicado: (2022)

H7 Hemagglutinin nanoparticles retain immunogenicity after >3 months of 25°C storage
por: Chang, Timothy Z., et al.
Publicado: (2018)

Virus-Like Particle Vaccine Protects against 2009 H1N1 Pandemic Influenza Virus in Mice
por: Quan, Fu-Shi, et al.
Publicado: (2010)

Genetic Assembly of Double‐Layered Fluorescent Protein Nanoparticles for Cancer Targeting and Imaging
por: Kim, Seong‐Eun, et al.
Publicado: (2017)

Polycationic HA/CpG Nanoparticles Induce Cross-Protective Influenza Immunity in Mice
por: Dong, Chunhong, et al.
Publicado: (2022)

Broad cross protection by recombinant live attenuated influenza H3N2 seasonal virus expressing conserved M2 extracellular domain in a chimeric hemagglutinin
por: Park, Bo Ryoung, et al.
Publicado: (2021)

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses
por: Kanekiyo, Masaru, et al.
Publicado: (2019)

Enhanced Immunogenicity of Stabilized Trimeric Soluble Influenza Hemagglutinin
por: Weldon, William C., et al.
Publicado: (2010)

Stabilization of Influenza Vaccine Enhances Protection by Microneedle Delivery in the Mouse Skin
por: Quan, Fu-Shi, et al.
Publicado: (2009)

Protective Effect of Ginseng Polysaccharides on Influenza Viral Infection
por: Yoo, Dae-Goon, et al.
Publicado: (2012)

Effect of Osmotic Pressure on the Stability of Whole Inactivated Influenza Vaccine for Coating on Microneedles
por: Choi, Hyo-Jick, et al.
Publicado: (2015)

Virus-Like Particles Containing the Tetrameric Ectodomain of Influenza Matrix Protein 2 and Flagellin Induce Heterosubtypic Protection in Mice
por: Wang, Li, et al.
Publicado: (2013)

Electrically tunable single- and few-layer MoS(2) nanoelectromechanical systems with broad dynamic range
por: Lee, Jaesung, et al.
Publicado: (2018)

Systemic toxicity induced by aggregated layered double hydroxide nanoparticles
por: Yan, Mina, et al.
Publicado: (2017)

Broadly-Reactive Neutralizing and Non-neutralizing Antibodies Directed against the H7 Influenza Virus Hemagglutinin Reveal Divergent Mechanisms of Protection
por: Tan, Gene S., et al.
Publicado: (2016)

Passive Broad-Spectrum Influenza Immunoprophylaxis
por: Berry, Cassandra M., et al.
Publicado: (2014)

Tackling influenza with broadly neutralizing antibodies
por: Corti, Davide, et al.
Publicado: (2017)

Fabrication and Characterization of Cu Nanoparticles Dispersed on ZnAl-Layered Double Hydroxide Nanocatalysts for the Oxidation of Cyclohexane
por: Kirar, Jagat Singh, et al.
Publicado: (2022)

Early Divergence, Broad Distribution, and High Diversity of Animal Chitin Synthases
por: Zakrzewski, Anne-C., et al.
Publicado: (2014)

A chimeric influenza hemagglutinin delivered by parainfluenza virus 5 vector induces broadly protective immunity against genetically divergent influenza a H1 viruses in swine
por: Li, Zhuo, et al.
Publicado: (2020)

Interactions between Layered Double Hydroxide Nanoparticles and Egg Yolk Lecithin Liposome Membranes
por: Liu, Bin, et al.
Publicado: (2023)

Changes in Human Langerhans Cells Following Intradermal Injection of Influenza Virus-Like Particle Vaccines
por: Pearton, Marc, et al.
Publicado: (2010)

Host‐ and pathogen‐derived adjuvant coatings on protein nanoparticle vaccines
por: Chang, Timothy Z., et al.
Publicado: (2017)

Double-Layer Fatty Acid Nanoparticles as a Multiplatform for Diagnostics and Therapy
por: Salvador, María, et al.
Publicado: (2022)

Correction: Changes in Human Langerhans Cells Following Intradermal Injection of Influenza Virus-Like Particle Vaccines
por: Pearton, Marc, et al.
Publicado: (2010)

CCL28 chemokine: An anchoring point bridging innate and adaptive immunity
por: Mohan, Teena, et al.
Publicado: (2017)

Host responses from innate to adaptive immunity after vaccination: Molecular and cellular events
por: Kang, Sang-Moo, et al.
Publicado: (2009)

Multi-Layered Bipolar Ionic Diode Working in Broad Range Ion Concentration
por: Kim, Jaehyun, et al.
Publicado: (2023)

Layered Double Hydroxide Nanotransporter for Molecule Delivery to Intact Plant Cells
por: Bao, Wenlong, et al.
Publicado: (2016)

Sublingual Immunization with M2-Based Vaccine Induces Broad Protective Immunity against Influenza
por: Shim, Byoung-Shik, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_vfjnjdt0se3ldtsq91lnmthuro