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Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials

Antibiotic resistance poses rapidly increasing global problems in combatting multidrug-resistant (MDR) infectious diseases like MDR tuberculosis, prompting for novel approaches including host-directed therapies (HDT). Intracellular pathogens like Salmonellae and Mycobacterium tuberculosis (Mtb) expl...

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Detalles Bibliográficos
Autores principales:	Korbee, Cornelis J., Heemskerk, Matthias T., Kocev, Dragi, van Strijen, Elisabeth, Rabiee, Omid, Franken, Kees L. M. C., Wilson, Louis, Savage, Nigel D. L., Džeroski, Sašo, Haks, Mariëlle C., Ottenhoff, Tom H. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783939/ https://www.ncbi.nlm.nih.gov/pubmed/29367740 http://dx.doi.org/10.1038/s41467-017-02777-6

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