Olfactory receptors are expressed in pancreatic β-cells and promote glucose-stimulated insulin secretion

Olfactory receptors (ORs) mediate olfactory chemo-sensation in OR neurons. Herein, we have demonstrated that the OR chemo-sensing machinery functions in pancreatic β-cells and modulates insulin secretion. First, we found several OR isoforms, including OLFR15 and OLFR821, to be expressed in pancreati...

Descripción completa

Detalles Bibliográficos
Autores principales: Munakata, Yuichiro, Yamada, Tetsuya, Imai, Junta, Takahashi, Kei, Tsukita, Sohei, Shirai, Yuta, Kodama, Shinjiro, Asai, Yoichiro, Sugisawa, Takashi, Chiba, Yumiko, Kaneko, Keizo, Uno, Kenji, Sawada, Shojiro, Hatakeyama, Hiroyasu, Kanzaki, Makoto, Miyazaki, Jun-ichi, Oka, Yoshitomo, Katagiri, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784078/
https://www.ncbi.nlm.nih.gov/pubmed/29367680
http://dx.doi.org/10.1038/s41598-018-19765-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784078/
https://www.ncbi.nlm.nih.gov/pubmed/29367680
http://dx.doi.org/10.1038/s41598-018-19765-5

Ejemplares similares