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Vascular endothelial effects of collaborative binding to platelet/endothelial cell adhesion molecule-1 (PECAM-1)

Targeting drugs to endothelial cells has shown the ability to improve outcomes in animal models of inflammatory, ischemic and thrombotic diseases. Previous studies have revealed that certain pairs of ligands (antibodies and antibody fragments) specific for adjacent, but distinct, epitopes on PECAM-1...

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Detalles Bibliográficos
Autores principales: Kiseleva, Raisa Yu., Greineder, C. F., Villa, C. H., Marcos-Contreras, O. A., Hood, E. D., Shuvaev, V. V., DeLisser, H. M., Muzykantov, V. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784113/
https://www.ncbi.nlm.nih.gov/pubmed/29367646
http://dx.doi.org/10.1038/s41598-018-20027-7