Cargando…
Vascular endothelial effects of collaborative binding to platelet/endothelial cell adhesion molecule-1 (PECAM-1)
Targeting drugs to endothelial cells has shown the ability to improve outcomes in animal models of inflammatory, ischemic and thrombotic diseases. Previous studies have revealed that certain pairs of ligands (antibodies and antibody fragments) specific for adjacent, but distinct, epitopes on PECAM-1...
Autores principales: | Kiseleva, Raisa Yu., Greineder, C. F., Villa, C. H., Marcos-Contreras, O. A., Hood, E. D., Shuvaev, V. V., DeLisser, H. M., Muzykantov, V. R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784113/ https://www.ncbi.nlm.nih.gov/pubmed/29367646 http://dx.doi.org/10.1038/s41598-018-20027-7 |
Ejemplares similares
-
Mechanism of Collaborative Enhancement of Binding of Paired Antibodies to Distinct Epitopes of Platelet Endothelial Cell Adhesion Molecule-1
por: Kiseleva, Raisa, et al.
Publicado: (2017) -
Collaborative Enhancement of Antibody Binding to Distinct PECAM-1 Epitopes Modulates Endothelial Targeting
por: Chacko, Ann-Marie, et al.
Publicado: (2012) -
Tyrosine Residue in Exon 14 of the Cytoplasmic Domain of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1/CD31) Regulates Ligand Binding Specificity
por: Famiglietti, Julie, et al.
Publicado: (1997) -
Influence of PECAM‐1 ligand interactions on PECAM‐1‐dependent cell motility and filopodia extension
por: Abraham, Valsamma, et al.
Publicado: (2016) -
The new frontiers of the targeted interventions in the pulmonary vasculature: precision and safety (2017 Grover Conference Series)
por: Brenner, Jacob S., et al.
Publicado: (2017)