Variants of the 5′-terminal region of p53 mRNA influence the ribosomal scanning and translation efficiency

The p53 protein is one of the major cell cycle regulators. The protein is expressed as at least twelve protein isoforms resulting from the use of alternative promoters, alternative splicing or downstream initiation codons. Importantly, there is growing evidence that translation initiation of p53 mRN...

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Detalles Bibliográficos
Autores principales: Zydowicz-Machtel, Paulina, Swiatkowska, Agata, Popenda, Łukasz, Gorska, Agnieszka, Ciesiołka, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784139/
https://www.ncbi.nlm.nih.gov/pubmed/29367734
http://dx.doi.org/10.1038/s41598-018-20010-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784139/
https://www.ncbi.nlm.nih.gov/pubmed/29367734
http://dx.doi.org/10.1038/s41598-018-20010-2

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