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Variants of the 5′-terminal region of p53 mRNA influence the ribosomal scanning and translation efficiency
The p53 protein is one of the major cell cycle regulators. The protein is expressed as at least twelve protein isoforms resulting from the use of alternative promoters, alternative splicing or downstream initiation codons. Importantly, there is growing evidence that translation initiation of p53 mRN...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784139/ https://www.ncbi.nlm.nih.gov/pubmed/29367734 http://dx.doi.org/10.1038/s41598-018-20010-2 |