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Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals

Where disease threatens endangered wildlife populations, substantial resources are required for management actions such as vaccination. While network models provide a promising tool for identifying key spreaders and prioritizing efforts to maximize efficiency, population-scale vaccination remains ra...

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Autores principales: Robinson, Stacie J., Barbieri, Michelle M., Murphy, Samantha, Baker, Jason D., Harting, Albert L., Craft, Meggan E., Littnan, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784189/
https://www.ncbi.nlm.nih.gov/pubmed/29321294
http://dx.doi.org/10.1098/rspb.2017.1899
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author Robinson, Stacie J.
Barbieri, Michelle M.
Murphy, Samantha
Baker, Jason D.
Harting, Albert L.
Craft, Meggan E.
Littnan, Charles L.
author_facet Robinson, Stacie J.
Barbieri, Michelle M.
Murphy, Samantha
Baker, Jason D.
Harting, Albert L.
Craft, Meggan E.
Littnan, Charles L.
author_sort Robinson, Stacie J.
collection PubMed
description Where disease threatens endangered wildlife populations, substantial resources are required for management actions such as vaccination. While network models provide a promising tool for identifying key spreaders and prioritizing efforts to maximize efficiency, population-scale vaccination remains rare, providing few opportunities to evaluate performance of model-informed strategies under realistic scenarios. Because the endangered Hawaiian monk seal could be heavily impacted by disease threats such as morbillivirus, we implemented a prophylactic vaccination programme. We used contact networks to prioritize vaccinating animals with high contact rates. We used dynamic network models to simulate morbillivirus outbreaks under real and idealized vaccination scenarios. We then evaluated the efficacy of model recommendations in this real-world vaccination project. We found that deviating from the model recommendations decreased the efficiency; requiring 44% more vaccinations to achieve a given decrease in outbreak size. However, we gained protection more quickly by vaccinating available animals rather than waiting to encounter priority seals. This work demonstrates the value of network models, but also makes trade-offs clear. If vaccines were limited but time was ample, vaccinating only priority animals would maximize herd protection. However, where time is the limiting factor, vaccinating additional lower-priority animals could more quickly protect the population.
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spelling pubmed-57841892018-01-30 Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals Robinson, Stacie J. Barbieri, Michelle M. Murphy, Samantha Baker, Jason D. Harting, Albert L. Craft, Meggan E. Littnan, Charles L. Proc Biol Sci Ecology Where disease threatens endangered wildlife populations, substantial resources are required for management actions such as vaccination. While network models provide a promising tool for identifying key spreaders and prioritizing efforts to maximize efficiency, population-scale vaccination remains rare, providing few opportunities to evaluate performance of model-informed strategies under realistic scenarios. Because the endangered Hawaiian monk seal could be heavily impacted by disease threats such as morbillivirus, we implemented a prophylactic vaccination programme. We used contact networks to prioritize vaccinating animals with high contact rates. We used dynamic network models to simulate morbillivirus outbreaks under real and idealized vaccination scenarios. We then evaluated the efficacy of model recommendations in this real-world vaccination project. We found that deviating from the model recommendations decreased the efficiency; requiring 44% more vaccinations to achieve a given decrease in outbreak size. However, we gained protection more quickly by vaccinating available animals rather than waiting to encounter priority seals. This work demonstrates the value of network models, but also makes trade-offs clear. If vaccines were limited but time was ample, vaccinating only priority animals would maximize herd protection. However, where time is the limiting factor, vaccinating additional lower-priority animals could more quickly protect the population. The Royal Society 2018-01-10 2018-01-10 /pmc/articles/PMC5784189/ /pubmed/29321294 http://dx.doi.org/10.1098/rspb.2017.1899 Text en © 2018 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Ecology
Robinson, Stacie J.
Barbieri, Michelle M.
Murphy, Samantha
Baker, Jason D.
Harting, Albert L.
Craft, Meggan E.
Littnan, Charles L.
Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals
title Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals
title_full Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals
title_fullStr Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals
title_full_unstemmed Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals
title_short Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals
title_sort model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered hawaiian monk seals
topic Ecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784189/
https://www.ncbi.nlm.nih.gov/pubmed/29321294
http://dx.doi.org/10.1098/rspb.2017.1899
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