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Complement C5a Receptor 1 Exacerbates the Pathophysiology of N. meningitidis Sepsis and Is a Potential Target for Disease Treatment
Sepsis caused by Neisseria meningitidis (meningococcus) is a rapidly progressing, life-threatening disease. Because its initial symptoms are rather unspecific, medical attention is often sought too late, i.e., when the systemic inflammatory response is already unleashed. This in turn limits the succ...
Autores principales: | Herrmann, Johannes B., Muenstermann, Marcel, Strobel, Lea, Schubert-Unkmeir, Alexandra, Woodruff, Trent M., Gray-Owen, Scott D., Klos, Andreas, Johswich, Kay O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784250/ https://www.ncbi.nlm.nih.gov/pubmed/29362231 http://dx.doi.org/10.1128/mBio.01755-17 |
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