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Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence
Candida albicans is an opportunistic fungal pathogen responsible for superficial and life-threatening infections in humans. During mucosal infection, C. albicans undergoes a morphological transition from yeast to invasive filamentous hyphae that secrete candidalysin, a 31-amino-acid peptide toxin re...
Autores principales: | Richardson, Jonathan P., Mogavero, Selene, Moyes, David L., Blagojevic, Mariana, Krüger, Thomas, Verma, Akash H., Coleman, Bianca M., De La Cruz Diaz, Jacinto, Schulz, Daniela, Ponde, Nicole O., Carrano, Giulia, Kniemeyer, Olaf, Wilson, Duncan, Bader, Oliver, Enoiu, Simona I., Ho, Jemima, Kichik, Nessim, Gaffen, Sarah L., Hube, Bernhard, Naglik, Julian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784256/ https://www.ncbi.nlm.nih.gov/pubmed/29362237 http://dx.doi.org/10.1128/mBio.02178-17 |
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