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Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence

Candida albicans is an opportunistic fungal pathogen responsible for superficial and life-threatening infections in humans. During mucosal infection, C. albicans undergoes a morphological transition from yeast to invasive filamentous hyphae that secrete candidalysin, a 31-amino-acid peptide toxin re...

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Detalles Bibliográficos
Autores principales: Richardson, Jonathan P., Mogavero, Selene, Moyes, David L., Blagojevic, Mariana, Krüger, Thomas, Verma, Akash H., Coleman, Bianca M., De La Cruz Diaz, Jacinto, Schulz, Daniela, Ponde, Nicole O., Carrano, Giulia, Kniemeyer, Olaf, Wilson, Duncan, Bader, Oliver, Enoiu, Simona I., Ho, Jemima, Kichik, Nessim, Gaffen, Sarah L., Hube, Bernhard, Naglik, Julian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784256/
https://www.ncbi.nlm.nih.gov/pubmed/29362237
http://dx.doi.org/10.1128/mBio.02178-17

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