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Mechanistic insights into the detection of free fatty and bile acids by ileal glucagon-like peptide-1 secreting cells

OBJECTIVES: The aim of this study was to investigate the electrical properties of ileal Glucagon-like peptide 1 (GLP-1) secreting L-cells using murine organoid cultures and the electrophysiological and intracellular signaling pathways recruited following activation of the G(αq)-coupled free fatty ac...

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Detalles Bibliográficos
Autores principales:	Goldspink, Deborah A., Lu, Van B., Billing, Lawrence J., Larraufie, Pierre, Tolhurst, Gwen, Gribble, Fiona M., Reimann, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784317/ https://www.ncbi.nlm.nih.gov/pubmed/29167062 http://dx.doi.org/10.1016/j.molmet.2017.11.005

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