Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase

OBJECTIVE: Leptin is a cytokine produced by adipose tissue that acts mainly on the hypothalamus to regulate appetite and energy homeostasis. Previous studies revealed that the leptin receptor is expressed not only in neurons, but also in glial cells. Microglia are resident immune cells in the brain...

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Detalles Bibliográficos
Autores principales: Gao, Yuanqing, Vidal-Itriago, Andrés, Milanova, Irina, Korpel, Nikita L., Kalsbeek, Martin J., Tom, Robby Zachariah, Kalsbeek, Andries, Hofmann, Susanna M., Yi, Chun-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784319/
https://www.ncbi.nlm.nih.gov/pubmed/29174000
http://dx.doi.org/10.1016/j.molmet.2017.11.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784319/
https://www.ncbi.nlm.nih.gov/pubmed/29174000
http://dx.doi.org/10.1016/j.molmet.2017.11.003

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