Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation

OBJECTIVE: We examined whether skeletal muscle overexpression of PGC-1α1 or PGC-1α4 affected myokine secretion and neuromuscular junction (NMJ) formation. METHODS: A microfluidic device was used to model endocrine signaling and NMJ formation between primary mouse myoblast-derived myotubes and embryo...

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Detalles Bibliográficos
Autores principales: Mills, Richard, Taylor-Weiner, Hermes, Correia, Jorge C., Agudelo, Leandro Z., Allodi, Ilary, Kolonelou, Christina, Martinez-Redondo, Vicente, Ferreira, Duarte M.S., Nichterwitz, Susanne, Comley, Laura H., Lundin, Vanessa, Hedlund, Eva, Ruas, Jorge L., Teixeira, Ana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784328/
https://www.ncbi.nlm.nih.gov/pubmed/29157948
http://dx.doi.org/10.1016/j.molmet.2017.11.001

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