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Engineering β-sheets employing N-methylated heterochiral amino acids
There is a lack of functional group diversity in the reverse turn motifs nucleating a β-sheet conformation in designed peptides, proteins and foldamers. The majority of these sequences consist of d-Pro–l-Pro, d-Pro–Gly or Asn–Gly as the turn inducing motif restricting their biological application an...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784515/ https://www.ncbi.nlm.nih.gov/pubmed/29449932 http://dx.doi.org/10.1039/c6sc00518g |