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Vascular medicine and thrombectomy in stroke

The treatment of stroke caused by intracranial vessel occlusion with intravenous recombinant tissue plasminogen activator (rt-PA) was the only evidence-based treatment option for a long time. Nevertheless the response rate was disappointing in large vessel occlusions. Five studies that evaluated the...

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Detalles Bibliográficos
Autores principales: Fischer, Sebastian, Weber, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784516/
https://www.ncbi.nlm.nih.gov/pubmed/29399050
http://dx.doi.org/10.1177/1756285617742082
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author Fischer, Sebastian
Weber, Werner
author_facet Fischer, Sebastian
Weber, Werner
author_sort Fischer, Sebastian
collection PubMed
description The treatment of stroke caused by intracranial vessel occlusion with intravenous recombinant tissue plasminogen activator (rt-PA) was the only evidence-based treatment option for a long time. Nevertheless the response rate was disappointing in large vessel occlusions. Five studies that evaluated the efficacy of mechanical thrombectomy published in 2015 proved a significant clinical benefit for selected patients suffering from acute ischemic stroke. These results are the basis for extensive technical, institutional, and personal structural changes in the neurovascular field of stroke treatment. This review gives an overview of the current status of mechanical thrombectomy and future expectations and challenges are discussed.
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spelling pubmed-57845162018-02-02 Vascular medicine and thrombectomy in stroke Fischer, Sebastian Weber, Werner Ther Adv Neurol Disord Review The treatment of stroke caused by intracranial vessel occlusion with intravenous recombinant tissue plasminogen activator (rt-PA) was the only evidence-based treatment option for a long time. Nevertheless the response rate was disappointing in large vessel occlusions. Five studies that evaluated the efficacy of mechanical thrombectomy published in 2015 proved a significant clinical benefit for selected patients suffering from acute ischemic stroke. These results are the basis for extensive technical, institutional, and personal structural changes in the neurovascular field of stroke treatment. This review gives an overview of the current status of mechanical thrombectomy and future expectations and challenges are discussed. SAGE Publications 2017-11-22 /pmc/articles/PMC5784516/ /pubmed/29399050 http://dx.doi.org/10.1177/1756285617742082 Text en © The Author(s), 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Fischer, Sebastian
Weber, Werner
Vascular medicine and thrombectomy in stroke
title Vascular medicine and thrombectomy in stroke
title_full Vascular medicine and thrombectomy in stroke
title_fullStr Vascular medicine and thrombectomy in stroke
title_full_unstemmed Vascular medicine and thrombectomy in stroke
title_short Vascular medicine and thrombectomy in stroke
title_sort vascular medicine and thrombectomy in stroke
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784516/
https://www.ncbi.nlm.nih.gov/pubmed/29399050
http://dx.doi.org/10.1177/1756285617742082
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