ISD3: a particokinetic model for predicting the combined effects of particle sedimentation, diffusion and dissolution on cellular dosimetry for in vitro systems

BACKGROUND: The development of particokinetic models describing the delivery of insoluble or poorly soluble nanoparticles to cells in liquid cell culture systems has improved the basis for dose-response analysis, hazard ranking from high-throughput systems, and now allows for translation of exposure...

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Detalles Bibliográficos
Autores principales: Thomas, Dennis G., Smith, Jordan N., Thrall, Brian D., Baer, Donald R., Jolley, Hadley, Munusamy, Prabhakaran, Kodali, Vamsi, Demokritou, Philip, Cohen, Joel, Teeguarden, Justin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784555/
https://www.ncbi.nlm.nih.gov/pubmed/29368623
http://dx.doi.org/10.1186/s12989-018-0243-7

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