Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review

Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological...

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Autores principales: Subramanian, Muthiah, Harikrishnan, M.S., Prabhu, Mukund A., Pai, Praveen G., Shekhar, Saritha S., Natarajan, Kumaraswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784606/
https://www.ncbi.nlm.nih.gov/pubmed/29231821
http://dx.doi.org/10.1016/j.ipej.2017.07.005
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author Subramanian, Muthiah
Harikrishnan, M.S.
Prabhu, Mukund A.
Pai, Praveen G.
Shekhar, Saritha S.
Natarajan, Kumaraswamy
author_facet Subramanian, Muthiah
Harikrishnan, M.S.
Prabhu, Mukund A.
Pai, Praveen G.
Shekhar, Saritha S.
Natarajan, Kumaraswamy
author_sort Subramanian, Muthiah
collection PubMed
description Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological studies induced typical AVNRT, which was successfully eliminated by radiofrequency ablation in all of them. Of the 22 reported cases, 96% had typical (slow-fast) variant of AVNRT. The predominant pattern of inheritance appears to be autosomal dominant, though other patterns may exist. Further research is needed to understand the genetic influence of AVNRT and its pathophysiology.
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spelling pubmed-57846062018-01-29 Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review Subramanian, Muthiah Harikrishnan, M.S. Prabhu, Mukund A. Pai, Praveen G. Shekhar, Saritha S. Natarajan, Kumaraswamy Indian Pacing Electrophysiol J Original Article Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological studies induced typical AVNRT, which was successfully eliminated by radiofrequency ablation in all of them. Of the 22 reported cases, 96% had typical (slow-fast) variant of AVNRT. The predominant pattern of inheritance appears to be autosomal dominant, though other patterns may exist. Further research is needed to understand the genetic influence of AVNRT and its pathophysiology. Elsevier 2017-07-10 /pmc/articles/PMC5784606/ /pubmed/29231821 http://dx.doi.org/10.1016/j.ipej.2017.07.005 Text en Copyright © 2017, Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Subramanian, Muthiah
Harikrishnan, M.S.
Prabhu, Mukund A.
Pai, Praveen G.
Shekhar, Saritha S.
Natarajan, Kumaraswamy
Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title_full Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title_fullStr Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title_full_unstemmed Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title_short Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title_sort familial atrioventricular nodal re-entrant tachycardia: a case seriers and a systematic review
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784606/
https://www.ncbi.nlm.nih.gov/pubmed/29231821
http://dx.doi.org/10.1016/j.ipej.2017.07.005
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