Cargando…

The CSF neurofilament light signature in rapidly progressive neurodegenerative dementias

BACKGROUND: Neurofilament light chain protein (NfL) is a surrogate biomarker of neurodegeneration that has never been systematically tested, either alone or in combination with other biomarkers, in atypical/rapidly progressive neurodegenerative dementias (NDs). METHODS: Using validated, commercially...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abu-Rumeileh, Samir, Capellari, Sabina, Stanzani-Maserati, Michelangelo, Polischi, Barbara, Martinelli, Paolo, Caroppo, Paola, Ladogana, Anna, Parchi, Piero
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784714/ https://www.ncbi.nlm.nih.gov/pubmed/29368621 http://dx.doi.org/10.1186/s13195-017-0331-1

Ejemplares similares

CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia
por: Abu-Rumeileh, Samir, et al.
Publicado: (2019)

Diagnostic Accuracy of a Combined Analysis of Cerebrospinal Fluid t-PrP, t-tau, p-tau, and Aβ(42) in the Differential Diagnosis of Creutzfeldt-Jakob Disease from Alzheimer’s Disease with Emphasis on Atypical Disease Variants
por: Abu Rumeileh, Samir, et al.
Publicado: (2016)

Antemortem CSF Aβ42/Aβ40 ratio predicts Alzheimer's disease pathology better than Aβ42 in rapidly progressive dementias
por: Baiardi, Simone, et al.
Publicado: (2018)

Diagnostic and prognostic performance of CSF α‐synuclein in prion disease in the context of rapidly progressive dementia
por: Mastrangelo, Andrea, et al.
Publicado: (2021)

Cerebrospinal Fluid and Blood Neurofilament Light Chain Protein in Prion Disease and Other Rapidly Progressive Dementias: Current State of the Art
por: Abu-Rumeileh, Samir, et al.
Publicado: (2021)

CSF SerpinA1 in Creutzfeldt–Jakob disease and frontotemporal lobar degeneration
por: Abu‐Rumeileh, Samir, et al.
Publicado: (2020)

Diagnostic value of plasma p-tau181, NfL, and GFAP in a clinical setting cohort of prevalent neurodegenerative dementias
por: Baiardi, Simone, et al.
Publicado: (2022)

Plasma and CSF Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: A Cross-Sectional and Longitudinal Study
por: Vacchiano, Veria, et al.
Publicado: (2021)

CSF Ubiquitin Levels Are Higher in Alzheimer’s Disease than in Frontotemporal Dementia and Reflect the Molecular Subtype in Prion Disease
por: Abu-Rumeileh, Samir, et al.
Publicado: (2020)

Diagnostic Value of the CSF α-Synuclein Real-Time Quaking-Induced Conversion Assay at the Prodromal MCI Stage of Dementia With Lewy Bodies
por: Rossi, Marcello, et al.
Publicado: (2021)

Prion-specific and surrogate CSF biomarkers in Creutzfeldt-Jakob disease: diagnostic accuracy in relation to molecular subtypes and analysis of neuropathological correlates of p-tau and Aβ42 levels
por: Lattanzio, Francesca, et al.
Publicado: (2017)

Neurofilament light chain and α-synuclein RT-QuIC as differential diagnostic biomarkers in parkinsonisms and related syndromes
por: Quadalti, Corinne, et al.
Publicado: (2021)

Diagnostic and prognostic value of cerebrospinal fluid SNAP-25 and neurogranin in Creutzfeldt-Jakob disease in a clinical setting cohort of rapidly progressive dementias
por: Bentivenga, Giuseppe Mario, et al.
Publicado: (2023)

Prodynorphin and Proenkephalin in Cerebrospinal Fluid of Sporadic Creutzfeldt–Jakob Disease
por: Abu-Rumeileh, Samir, et al.
Publicado: (2022)

Dementia-related genetic variants in an Italian population of early-onset Alzheimer’s disease
por: Bartoletti-Stella, Anna, et al.
Publicado: (2022)

Revisiting the Heidenhain Variant of Creutzfeldt-Jakob Disease: Evidence for Prion Type Variability Influencing Clinical Course and Laboratory Findings
por: Baiardi, Simone, et al.
Publicado: (2015)

Phenotypic Heterogeneity of Variably Protease-Sensitive Prionopathy: A Report of Three Cases Carrying Different Genotypes at PRNP Codon 129
por: Baiardi, Simone, et al.
Publicado: (2022)

Predicting conversion from mild cognitive impairment to Alzheimer's disease using brain (1)H-MRS and volumetric changes: A two- year retrospective follow-up study
por: Mitolo, Micaela, et al.
Publicado: (2019)

High diagnostic performance of plasma and cerebrospinal fluid beta‐synuclein for sporadic Creutzfeldt–Jakob disease
por: Abu‐Rumeileh, Samir, et al.
Publicado: (2023)

Neurofilaments in motor neuron disorders: towards promising diagnostic and prognostic biomarkers
por: Zucchi, Elisabetta, et al.
Publicado: (2020)

Defining the phenotypic spectrum of sporadic Creutzfeldt–Jakob disease MV2K: the kuru plaque type
por: Baiardi, Simone, et al.
Publicado: (2023)

Amyloid-Beta Co-Pathology Is a Major Determinant of the Elevated Plasma GFAP Values in Amyotrophic Lateral Sclerosis
por: Mastrangelo, Andrea, et al.
Publicado: (2023)

Is CSF neurofilament light chain measurement relevant for MS?
por: Matsui, Makoto
Publicado: (2020)

High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions
por: Franceschini, Alessia, et al.
Publicado: (2017)

Color Choice Preference in Cognitively Impaired Patients: A Look Inside Alzheimer’s Disease Through the Use of Lüscher Color Diagnostic
por: Stanzani Maserati, Michelangelo, et al.
Publicado: (2019)

Editorial: CSF and blood biomarkers in COVID-19 and other neuroinfectious diseases
por: Foschi, Matteo, et al.
Publicado: (2023)

In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC
por: Donadio, Vincenzo, et al.
Publicado: (2021)

CSF neurofilament light chain reflects corticospinal tract degeneration in ALS
por: Menke, Ricarda A L, et al.
Publicado: (2015)

Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures
por: Mielke, Michelle M., et al.
Publicado: (2019)

CSF Neurofilament Light Chain Elevation Predicts ALS Severity and Progression
por: Sun, Qionghua, et al.
Publicado: (2020)

Combination of serum and CSF neurofilament-light and neuroinflammatory biomarkers to evaluate ALS
por: Brodovitch, Alexandre, et al.
Publicado: (2021)

CSF Neurofilament Light Chain Concentrations Predict Outcome in Bacterial Meningitis
por: Chekrouni, Nora, et al.
Publicado: (2021)

Neurofilament light (NfL) as biomarker in serum and CSF in status epilepticus
por: Margraf, Nils G., et al.
Publicado: (2023)

Neurofilament proteins in axonal regeneration and neurodegenerative diseases☆
por: Wang, Haitao, et al.
Publicado: (2012)

Increased Neurofilament Light Chain Blood Levels in Neurodegenerative Neurological Diseases
por: Gaiottino, Johanna, et al.
Publicado: (2013)

The First Sporadic Creutzfeldt–Jakob Disease Case with a Rare Molecular Subtype VV1 and 1-Octapeptide Repeat Deletion in PRNP
por: Areškevičiūtė, Aušrinė, et al.
Publicado: (2021)

The Use of Real-Time Quaking-Induced Conversion for the Diagnosis of Human Prion Diseases
por: Poleggi, Anna, et al.
Publicado: (2022)

Elevated neurofilament light chain CSF/serum ratio indicates impaired CSF outflow in idiopathic intracranial hypertension
por: Engel, Sinah, et al.
Publicado: (2023)

Fingolimod and CSF neurofilament light chain levels in relapsing-remitting multiple sclerosis
por: Kuhle, Jens, et al.
Publicado: (2015)

CSF Neurofilament Light Chain but not FLT3 Ligand Discriminates Parkinsonian Disorders
por: Herbert, Megan K., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_0578o8qp2bmd0ustc3hh5is92h