An Integrated Native Mass Spectrometry and Top-Down Proteomics Method that Connects Sequence to Structure and Function of Macromolecular Complexes

Mass spectrometry (MS) has become a crucial technique for the analysis of protein complexes. Native MS has traditionally examined protein subunit arrangements, while proteomics MS has focused on sequence identification. These two techniques are usually performed separately without harvesting the syn...

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Detalles Bibliográficos
Autores principales: Li, Huilin, Nguyen, Hong Hanh, Ogorzalek Loo, Rachel R., Campuzano, Iain D. G., Loo, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784781/
https://www.ncbi.nlm.nih.gov/pubmed/29359744
http://dx.doi.org/10.1038/nchem.2908

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