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Programmable autonomous synthesis of single-stranded DNA

DNA performs diverse functional roles in biology, nanotechnology, and biotechnology, but current methods for autonomously synthesizing arbitrary single-stranded DNA are limited. Here, we introduce the concept of Primer Exchange Reaction (PER) cascades, which grow nascent single-stranded DNA with use...

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Detalles Bibliográficos
Autores principales: Kishi, Jocelyn Y., Schaus, Thomas E., Gopalkrishnan, Nikhil, Xuan, Feng, Yin, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784857/
https://www.ncbi.nlm.nih.gov/pubmed/29359755
http://dx.doi.org/10.1038/nchem.2872