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Enhanced gastric retention and drug release via development of novel floating microspheres based on Eudragit E100 and polycaprolactone: synthesis and in vitro evaluation

Eudragit E 100 and polycaprolactone (PCL) floating microspheres for enhanced gastric retention and drug release were successfully prepared by oil in water solvent evaporation method. Metronidazole benzoate, an anti-protozoal drug, was used as a model drug. Polyvinyl alcohol was used as an emulsifier...

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Detalles Bibliográficos
Autores principales: Farooq, Umar, Khan, Samiullah, Nawaz, Shahid, Ranjha, Nazar Mohammad, Haider, Malik Salman, Khan, Muhammad Muzamil, Dar, Eshwa, Nawaz, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784876/
https://www.ncbi.nlm.nih.gov/pubmed/29491813
http://dx.doi.org/10.1080/15685551.2017.1326702