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Hepatitis E prevalence in a sexual high-risk population compared to the general population
Transmission routes of the hepatitis E virus (HEV) are under debate. Here, we studied possible sexual transmission by comparing HEV prevalence in a Dutch sexual high-risk population (n = 1,482) with that in a general population (n = 1,487) while assessing sociodemographic and sexual risk factors. Ov...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784977/ https://www.ncbi.nlm.nih.gov/pubmed/29370254 http://dx.doi.org/10.1371/journal.pone.0191798 |
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author | Heil, Jeanne Hoebe, Christian J. P. A. van Loo, Inge H. M. Cals, Jochen W. L. van Liere, Geneviève A. F. S. Dukers-Muijrers, Nicole H. T. M. |
author_facet | Heil, Jeanne Hoebe, Christian J. P. A. van Loo, Inge H. M. Cals, Jochen W. L. van Liere, Geneviève A. F. S. Dukers-Muijrers, Nicole H. T. M. |
author_sort | Heil, Jeanne |
collection | PubMed |
description | Transmission routes of the hepatitis E virus (HEV) are under debate. Here, we studied possible sexual transmission by comparing HEV prevalence in a Dutch sexual high-risk population (n = 1,482) with that in a general population (n = 1,487) while assessing sociodemographic and sexual risk factors. Overall prevalence of anti-HEV IgG of 18.9% (n = 562) was, adjusting for confounders, similar between the two populations (p = 0.44). Prevalence was higher with each year’s increase in age (adjusted OR: 1.03, 95%CI: 1.02–1.04, p<0.01), among men (adjusted OR: 1.24, 95%CI: 1.02–1.50, p = 0.03) and among individuals diagnosed with sexually transmitted infections (adjusted OR: 1.60, 95%CI: 1.02–2.49, p = 0.04). Our results only hint at the possibility of a sexual transmission route for HEV given higher rates in those with chlamydia and/or gonorrheal infections. Sexual transmission is not a dominant transmission route, as its prevalence was not higher for the sexual high-risk population than for the general population. |
format | Online Article Text |
id | pubmed-5784977 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-57849772018-02-09 Hepatitis E prevalence in a sexual high-risk population compared to the general population Heil, Jeanne Hoebe, Christian J. P. A. van Loo, Inge H. M. Cals, Jochen W. L. van Liere, Geneviève A. F. S. Dukers-Muijrers, Nicole H. T. M. PLoS One Research Article Transmission routes of the hepatitis E virus (HEV) are under debate. Here, we studied possible sexual transmission by comparing HEV prevalence in a Dutch sexual high-risk population (n = 1,482) with that in a general population (n = 1,487) while assessing sociodemographic and sexual risk factors. Overall prevalence of anti-HEV IgG of 18.9% (n = 562) was, adjusting for confounders, similar between the two populations (p = 0.44). Prevalence was higher with each year’s increase in age (adjusted OR: 1.03, 95%CI: 1.02–1.04, p<0.01), among men (adjusted OR: 1.24, 95%CI: 1.02–1.50, p = 0.03) and among individuals diagnosed with sexually transmitted infections (adjusted OR: 1.60, 95%CI: 1.02–2.49, p = 0.04). Our results only hint at the possibility of a sexual transmission route for HEV given higher rates in those with chlamydia and/or gonorrheal infections. Sexual transmission is not a dominant transmission route, as its prevalence was not higher for the sexual high-risk population than for the general population. Public Library of Science 2018-01-25 /pmc/articles/PMC5784977/ /pubmed/29370254 http://dx.doi.org/10.1371/journal.pone.0191798 Text en © 2018 Heil et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Heil, Jeanne Hoebe, Christian J. P. A. van Loo, Inge H. M. Cals, Jochen W. L. van Liere, Geneviève A. F. S. Dukers-Muijrers, Nicole H. T. M. Hepatitis E prevalence in a sexual high-risk population compared to the general population |
title | Hepatitis E prevalence in a sexual high-risk population compared to the general population |
title_full | Hepatitis E prevalence in a sexual high-risk population compared to the general population |
title_fullStr | Hepatitis E prevalence in a sexual high-risk population compared to the general population |
title_full_unstemmed | Hepatitis E prevalence in a sexual high-risk population compared to the general population |
title_short | Hepatitis E prevalence in a sexual high-risk population compared to the general population |
title_sort | hepatitis e prevalence in a sexual high-risk population compared to the general population |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784977/ https://www.ncbi.nlm.nih.gov/pubmed/29370254 http://dx.doi.org/10.1371/journal.pone.0191798 |
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