Cargando…

Hepatitis E prevalence in a sexual high-risk population compared to the general population

Transmission routes of the hepatitis E virus (HEV) are under debate. Here, we studied possible sexual transmission by comparing HEV prevalence in a Dutch sexual high-risk population (n = 1,482) with that in a general population (n = 1,487) while assessing sociodemographic and sexual risk factors. Ov...

Descripción completa

Detalles Bibliográficos
Autores principales: Heil, Jeanne, Hoebe, Christian J. P. A., van Loo, Inge H. M., Cals, Jochen W. L., van Liere, Geneviève A. F. S., Dukers-Muijrers, Nicole H. T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784977/
https://www.ncbi.nlm.nih.gov/pubmed/29370254
http://dx.doi.org/10.1371/journal.pone.0191798
_version_ 1783295548207398912
author Heil, Jeanne
Hoebe, Christian J. P. A.
van Loo, Inge H. M.
Cals, Jochen W. L.
van Liere, Geneviève A. F. S.
Dukers-Muijrers, Nicole H. T. M.
author_facet Heil, Jeanne
Hoebe, Christian J. P. A.
van Loo, Inge H. M.
Cals, Jochen W. L.
van Liere, Geneviève A. F. S.
Dukers-Muijrers, Nicole H. T. M.
author_sort Heil, Jeanne
collection PubMed
description Transmission routes of the hepatitis E virus (HEV) are under debate. Here, we studied possible sexual transmission by comparing HEV prevalence in a Dutch sexual high-risk population (n = 1,482) with that in a general population (n = 1,487) while assessing sociodemographic and sexual risk factors. Overall prevalence of anti-HEV IgG of 18.9% (n = 562) was, adjusting for confounders, similar between the two populations (p = 0.44). Prevalence was higher with each year’s increase in age (adjusted OR: 1.03, 95%CI: 1.02–1.04, p<0.01), among men (adjusted OR: 1.24, 95%CI: 1.02–1.50, p = 0.03) and among individuals diagnosed with sexually transmitted infections (adjusted OR: 1.60, 95%CI: 1.02–2.49, p = 0.04). Our results only hint at the possibility of a sexual transmission route for HEV given higher rates in those with chlamydia and/or gonorrheal infections. Sexual transmission is not a dominant transmission route, as its prevalence was not higher for the sexual high-risk population than for the general population.
format Online
Article
Text
id pubmed-5784977
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-57849772018-02-09 Hepatitis E prevalence in a sexual high-risk population compared to the general population Heil, Jeanne Hoebe, Christian J. P. A. van Loo, Inge H. M. Cals, Jochen W. L. van Liere, Geneviève A. F. S. Dukers-Muijrers, Nicole H. T. M. PLoS One Research Article Transmission routes of the hepatitis E virus (HEV) are under debate. Here, we studied possible sexual transmission by comparing HEV prevalence in a Dutch sexual high-risk population (n = 1,482) with that in a general population (n = 1,487) while assessing sociodemographic and sexual risk factors. Overall prevalence of anti-HEV IgG of 18.9% (n = 562) was, adjusting for confounders, similar between the two populations (p = 0.44). Prevalence was higher with each year’s increase in age (adjusted OR: 1.03, 95%CI: 1.02–1.04, p<0.01), among men (adjusted OR: 1.24, 95%CI: 1.02–1.50, p = 0.03) and among individuals diagnosed with sexually transmitted infections (adjusted OR: 1.60, 95%CI: 1.02–2.49, p = 0.04). Our results only hint at the possibility of a sexual transmission route for HEV given higher rates in those with chlamydia and/or gonorrheal infections. Sexual transmission is not a dominant transmission route, as its prevalence was not higher for the sexual high-risk population than for the general population. Public Library of Science 2018-01-25 /pmc/articles/PMC5784977/ /pubmed/29370254 http://dx.doi.org/10.1371/journal.pone.0191798 Text en © 2018 Heil et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Heil, Jeanne
Hoebe, Christian J. P. A.
van Loo, Inge H. M.
Cals, Jochen W. L.
van Liere, Geneviève A. F. S.
Dukers-Muijrers, Nicole H. T. M.
Hepatitis E prevalence in a sexual high-risk population compared to the general population
title Hepatitis E prevalence in a sexual high-risk population compared to the general population
title_full Hepatitis E prevalence in a sexual high-risk population compared to the general population
title_fullStr Hepatitis E prevalence in a sexual high-risk population compared to the general population
title_full_unstemmed Hepatitis E prevalence in a sexual high-risk population compared to the general population
title_short Hepatitis E prevalence in a sexual high-risk population compared to the general population
title_sort hepatitis e prevalence in a sexual high-risk population compared to the general population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784977/
https://www.ncbi.nlm.nih.gov/pubmed/29370254
http://dx.doi.org/10.1371/journal.pone.0191798
work_keys_str_mv AT heiljeanne hepatitiseprevalenceinasexualhighriskpopulationcomparedtothegeneralpopulation
AT hoebechristianjpa hepatitiseprevalenceinasexualhighriskpopulationcomparedtothegeneralpopulation
AT vanlooingehm hepatitiseprevalenceinasexualhighriskpopulationcomparedtothegeneralpopulation
AT calsjochenwl hepatitiseprevalenceinasexualhighriskpopulationcomparedtothegeneralpopulation
AT vanlieregenevieveafs hepatitiseprevalenceinasexualhighriskpopulationcomparedtothegeneralpopulation
AT dukersmuijrersnicolehtm hepatitiseprevalenceinasexualhighriskpopulationcomparedtothegeneralpopulation