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Identification of an elaborate NK-specific system regulating HLA-C expression

The HLA-C gene appears to have evolved in higher primates to serve as a dominant source of ligands for the KIR2D family of inhibitory MHC class I receptors. The expression of NK cell-intrinsic MHC class I has been shown to regulate the murine Ly49 family of MHC class I receptors due to the interacti...

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Detalles Bibliográficos
Autores principales: Li, Hongchuan, Ivarsson, Martin A., Walker-Sperling, Victoria E., Subleski, Jeff, Johnson, Jenna K., Wright, Paul W., Carrington, Mary, Björkström, Niklas K., McVicar, Daniel W., Anderson, Stephen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785035/
https://www.ncbi.nlm.nih.gov/pubmed/29329284
http://dx.doi.org/10.1371/journal.pgen.1007163