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Burkholderia pseudomallei modulates host iron homeostasis to facilitate iron availability and intracellular survival
BACKGROUND: The control over iron homeostasis is critical in host-pathogen-interaction. Iron plays not only multiple roles for bacterial growth and pathogenicity, but also for modulation of innate immune responses. Hepcidin is a key regulator of host iron metabolism triggering degradation of the iro...
Autores principales: | Schmidt, Imke H. E., Gildhorn, Claudia, Böning, Martha A. L., Kulow, Vera A., Steinmetz, Ivo, Bast, Antje |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785036/ https://www.ncbi.nlm.nih.gov/pubmed/29329289 http://dx.doi.org/10.1371/journal.pntd.0006096 |
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