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Burkholderia pseudomallei modulates host iron homeostasis to facilitate iron availability and intracellular survival

BACKGROUND: The control over iron homeostasis is critical in host-pathogen-interaction. Iron plays not only multiple roles for bacterial growth and pathogenicity, but also for modulation of innate immune responses. Hepcidin is a key regulator of host iron metabolism triggering degradation of the iro...

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Detalles Bibliográficos
Autores principales: Schmidt, Imke H. E., Gildhorn, Claudia, Böning, Martha A. L., Kulow, Vera A., Steinmetz, Ivo, Bast, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785036/
https://www.ncbi.nlm.nih.gov/pubmed/29329289
http://dx.doi.org/10.1371/journal.pntd.0006096

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