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Complete pathologic response after chemoradiotherapy in a patient with rectal squamous cell carcinoma: a case report

Squamous cell carcinoma (SCC) of the rectum is a rare disease. A 59-year-old man presented with SCC of the middle rectum located 10 cm from the anus. The stage of the tumor was revealed to be T3N+M0. The patient received a combined treatment with cisplatin and fluorouracil in concomitance with exter...

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Detalles Bibliográficos
Autores principales: Sonia, Zaied, Amira, Daldoul, Hanene, Bhiri, Nouha, Ammar, Wiem, Khechine, Omar, Toumi, Ibtissem, Abbes, Salem Amina, Ben, Manel, Njima, Houda, Mhabrech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785164/
https://www.ncbi.nlm.nih.gov/pubmed/29372108
http://dx.doi.org/10.20892/j.issn.2095-3941.2017.0010
Descripción
Sumario:Squamous cell carcinoma (SCC) of the rectum is a rare disease. A 59-year-old man presented with SCC of the middle rectum located 10 cm from the anus. The stage of the tumor was revealed to be T3N+M0. The patient received a combined treatment with cisplatin and fluorouracil in concomitance with external radiation therapy. He then underwent an anterior resection of the rectum. The postoperative histopathological findings classified the tumor as ypT0N0 with cancer-free margins and lymph nodes. Treatment of SCC remains very challenging, and the acquisition of more consistent data is needed.