Brain metastasis in non-small cell lung cancer (NSCLC) patients with uncommon EGFR mutations: a report of seven cases and literature review

Brain metastasis (BM) arising from non-small cell lung cancer (NSCLC) with rare epidermal growth factor receptor (EGFR) mutations is quite rare. The prognosis and therapeutic effects of BM remain enigmatic. To the best of our knowledge, this is the first report to make a separate analysis of BM from...

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Detalles Bibliográficos
Autores principales: Er, Puchun, Zhang, Tian, Wang, Jing, Pang, Qingsong, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785170/
https://www.ncbi.nlm.nih.gov/pubmed/29372109
http://dx.doi.org/10.20892/j.issn.2095-3941.2017.0079
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author Er, Puchun
Zhang, Tian
Wang, Jing
Pang, Qingsong
Wang, Ping
author_facet Er, Puchun
Zhang, Tian
Wang, Jing
Pang, Qingsong
Wang, Ping
author_sort Er, Puchun
collection PubMed
description Brain metastasis (BM) arising from non-small cell lung cancer (NSCLC) with rare epidermal growth factor receptor (EGFR) mutations is quite rare. The prognosis and therapeutic effects of BM remain enigmatic. To the best of our knowledge, this is the first report to make a separate analysis of BM from NSCLC patients with original uncommon EGFR mutations. We retrospectively reviewed 7 cases of BM arising from 42 cases of uncommon EGFR mutated lung cancer in Tianjin Medical University Cancer Institute and Hospital. We also performed a literature review to assess therapeutic features and outcomes.
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spelling pubmed-57851702018-01-25 Brain metastasis in non-small cell lung cancer (NSCLC) patients with uncommon EGFR mutations: a report of seven cases and literature review Er, Puchun Zhang, Tian Wang, Jing Pang, Qingsong Wang, Ping Cancer Biol Med Case Report Brain metastasis (BM) arising from non-small cell lung cancer (NSCLC) with rare epidermal growth factor receptor (EGFR) mutations is quite rare. The prognosis and therapeutic effects of BM remain enigmatic. To the best of our knowledge, this is the first report to make a separate analysis of BM from NSCLC patients with original uncommon EGFR mutations. We retrospectively reviewed 7 cases of BM arising from 42 cases of uncommon EGFR mutated lung cancer in Tianjin Medical University Cancer Institute and Hospital. We also performed a literature review to assess therapeutic features and outcomes. Chinese Anti-Cancer Association 2017-11 /pmc/articles/PMC5785170/ /pubmed/29372109 http://dx.doi.org/10.20892/j.issn.2095-3941.2017.0079 Text en
spellingShingle Case Report
Er, Puchun
Zhang, Tian
Wang, Jing
Pang, Qingsong
Wang, Ping
Brain metastasis in non-small cell lung cancer (NSCLC) patients with uncommon EGFR mutations: a report of seven cases and literature review
title Brain metastasis in non-small cell lung cancer (NSCLC) patients with uncommon EGFR mutations: a report of seven cases and literature review
title_full Brain metastasis in non-small cell lung cancer (NSCLC) patients with uncommon EGFR mutations: a report of seven cases and literature review
title_fullStr Brain metastasis in non-small cell lung cancer (NSCLC) patients with uncommon EGFR mutations: a report of seven cases and literature review
title_full_unstemmed Brain metastasis in non-small cell lung cancer (NSCLC) patients with uncommon EGFR mutations: a report of seven cases and literature review
title_short Brain metastasis in non-small cell lung cancer (NSCLC) patients with uncommon EGFR mutations: a report of seven cases and literature review
title_sort brain metastasis in non-small cell lung cancer (nsclc) patients with uncommon egfr mutations: a report of seven cases and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785170/
https://www.ncbi.nlm.nih.gov/pubmed/29372109
http://dx.doi.org/10.20892/j.issn.2095-3941.2017.0079
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