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SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells
Single-stranded oligonucleotides (ssOligos) are efficiently taken up by living cells without the use of transfection reagents. This phenomenon called ‘gymnosis’ enables the sequence-specific silencing of target genes in various types of cells. Several antisense ssOligos are used for the treatment of...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785214/ https://www.ncbi.nlm.nih.gov/pubmed/28277980 http://dx.doi.org/10.1080/15476286.2017.1302641 |