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Determination of flutamide and two major metabolites using HPLC–DAD and HPTLC methods
Flutamide is a potential antineoplastic drug classified as an anti-androgen. It is a therapy for men with advanced prostate cancer, administered orally after which it undergoes extensively first pass metabolism in the liver with the production of several metabolites. These metabolites are predominan...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785457/ https://www.ncbi.nlm.nih.gov/pubmed/29372342 http://dx.doi.org/10.1186/s13065-018-0372-y |