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Regulation of haematopoietic multipotency by EZH1

All haematopoietic lineages circulating in the blood of adult mammals derive from multipotent haematopoietic stem cells (HSCs)(1). Haematopoiesis in the mammalian embryo stands in stark contrast, with lineage-restricted progenitors arising first, independently of HSCs, and HSCs emerging only later i...

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Detalles Bibliográficos
Autores principales: Vo, Linda T., Kinney, Melissa A., Liu, Xin, Zhang, Yuannyu, Barragan, Jessica, Sousa, Patricia M., Jha, Deepak K., Han, Areum, Cesana, Marcella, Shao, Zhen, North, Trista E., Orkin, Stuart H., Doulatov, Sergei, Xu, Jian, Daley, George Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785461/
https://www.ncbi.nlm.nih.gov/pubmed/29342143
http://dx.doi.org/10.1038/nature25435