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SEOM clinical guideline of diagnosis and management of low-grade glioma (2017)
Diffuse infiltrating low-grade gliomas include oligodendrogliomas and astrocytomas, and account for about 5% of all primary brain tumors. Treatment strategies for these low-grade gliomas in adults have recently changed. The 2016 World Health Organization (WHO) classification has updated the definiti...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785601/ https://www.ncbi.nlm.nih.gov/pubmed/29124520 http://dx.doi.org/10.1007/s12094-017-1790-3 |
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author | Sepúlveda-Sánchez, J. M. Muñoz Langa, J. Arráez, M. Á. Fuster, J. Hernández Laín, A. Reynés, G. Rodríguez González, V. Vicente, E. Vidal Denis, M. Gallego, Ó. |
author_facet | Sepúlveda-Sánchez, J. M. Muñoz Langa, J. Arráez, M. Á. Fuster, J. Hernández Laín, A. Reynés, G. Rodríguez González, V. Vicente, E. Vidal Denis, M. Gallego, Ó. |
author_sort | Sepúlveda-Sánchez, J. M. |
collection | PubMed |
description | Diffuse infiltrating low-grade gliomas include oligodendrogliomas and astrocytomas, and account for about 5% of all primary brain tumors. Treatment strategies for these low-grade gliomas in adults have recently changed. The 2016 World Health Organization (WHO) classification has updated the definition of these tumors to include their molecular characterization, including the presence of isocitrate dehydrogenase (IDH) mutation and 1p/19p codeletion. In this new classification, the histologic subtype of grade II-mixed oligoastrocytoma has also been eliminated. The precise optimal management of patients with low-grade glioma after resection remains to be determined. The risk–benefit ratio of adjuvant treatment must be weighed for each individual. |
format | Online Article Text |
id | pubmed-5785601 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-57856012018-02-01 SEOM clinical guideline of diagnosis and management of low-grade glioma (2017) Sepúlveda-Sánchez, J. M. Muñoz Langa, J. Arráez, M. Á. Fuster, J. Hernández Laín, A. Reynés, G. Rodríguez González, V. Vicente, E. Vidal Denis, M. Gallego, Ó. Clin Transl Oncol Clinical Guides in Oncology Diffuse infiltrating low-grade gliomas include oligodendrogliomas and astrocytomas, and account for about 5% of all primary brain tumors. Treatment strategies for these low-grade gliomas in adults have recently changed. The 2016 World Health Organization (WHO) classification has updated the definition of these tumors to include their molecular characterization, including the presence of isocitrate dehydrogenase (IDH) mutation and 1p/19p codeletion. In this new classification, the histologic subtype of grade II-mixed oligoastrocytoma has also been eliminated. The precise optimal management of patients with low-grade glioma after resection remains to be determined. The risk–benefit ratio of adjuvant treatment must be weighed for each individual. Springer International Publishing 2017-11-09 2018 /pmc/articles/PMC5785601/ /pubmed/29124520 http://dx.doi.org/10.1007/s12094-017-1790-3 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Clinical Guides in Oncology Sepúlveda-Sánchez, J. M. Muñoz Langa, J. Arráez, M. Á. Fuster, J. Hernández Laín, A. Reynés, G. Rodríguez González, V. Vicente, E. Vidal Denis, M. Gallego, Ó. SEOM clinical guideline of diagnosis and management of low-grade glioma (2017) |
title | SEOM clinical guideline of diagnosis and management of low-grade glioma (2017) |
title_full | SEOM clinical guideline of diagnosis and management of low-grade glioma (2017) |
title_fullStr | SEOM clinical guideline of diagnosis and management of low-grade glioma (2017) |
title_full_unstemmed | SEOM clinical guideline of diagnosis and management of low-grade glioma (2017) |
title_short | SEOM clinical guideline of diagnosis and management of low-grade glioma (2017) |
title_sort | seom clinical guideline of diagnosis and management of low-grade glioma (2017) |
topic | Clinical Guides in Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785601/ https://www.ncbi.nlm.nih.gov/pubmed/29124520 http://dx.doi.org/10.1007/s12094-017-1790-3 |
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