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SEOM clinical guidelines for anaplastic gliomas (2017)
The SEOM/GEINO clinical guidelines provide recommendations for radiological, and molecular diagnosis, treatment and follow-up of adult patients with anaplastic gliomas (AG). We followed the 2016 WHO classification which specifies the major diagnostic/prognostic and predictive value of IDH1/IDH2 miss...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785606/ https://www.ncbi.nlm.nih.gov/pubmed/29058264 http://dx.doi.org/10.1007/s12094-017-1762-7 |
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author | Balañá, C. Alonso, M. Hernandez, A. Perez-Segura, P. Pineda, E. Ramos, A. Sanchez, A. R. Teixidor, P. Verger, E. Benavides, M. |
author_facet | Balañá, C. Alonso, M. Hernandez, A. Perez-Segura, P. Pineda, E. Ramos, A. Sanchez, A. R. Teixidor, P. Verger, E. Benavides, M. |
author_sort | Balañá, C. |
collection | PubMed |
description | The SEOM/GEINO clinical guidelines provide recommendations for radiological, and molecular diagnosis, treatment and follow-up of adult patients with anaplastic gliomas (AG). We followed the 2016 WHO classification which specifies the major diagnostic/prognostic and predictive value of IDH1/IDH2 missense mutations and 1p/19q codeletions in AG. The diagnosis of anaplastic oligoastrocytoma is discouraged. Surgery, radiotherapy and chemotherapy with PCV or TMZ are the first-line standard of care for AG with slight modifications according to molecular variables. A multidisciplinary team is highly recommended in the management of these tumors. |
format | Online Article Text |
id | pubmed-5785606 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-57856062018-02-01 SEOM clinical guidelines for anaplastic gliomas (2017) Balañá, C. Alonso, M. Hernandez, A. Perez-Segura, P. Pineda, E. Ramos, A. Sanchez, A. R. Teixidor, P. Verger, E. Benavides, M. Clin Transl Oncol Clinical Guides in Oncology The SEOM/GEINO clinical guidelines provide recommendations for radiological, and molecular diagnosis, treatment and follow-up of adult patients with anaplastic gliomas (AG). We followed the 2016 WHO classification which specifies the major diagnostic/prognostic and predictive value of IDH1/IDH2 missense mutations and 1p/19q codeletions in AG. The diagnosis of anaplastic oligoastrocytoma is discouraged. Surgery, radiotherapy and chemotherapy with PCV or TMZ are the first-line standard of care for AG with slight modifications according to molecular variables. A multidisciplinary team is highly recommended in the management of these tumors. Springer International Publishing 2017-10-20 2018 /pmc/articles/PMC5785606/ /pubmed/29058264 http://dx.doi.org/10.1007/s12094-017-1762-7 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Clinical Guides in Oncology Balañá, C. Alonso, M. Hernandez, A. Perez-Segura, P. Pineda, E. Ramos, A. Sanchez, A. R. Teixidor, P. Verger, E. Benavides, M. SEOM clinical guidelines for anaplastic gliomas (2017) |
title | SEOM clinical guidelines for anaplastic gliomas (2017) |
title_full | SEOM clinical guidelines for anaplastic gliomas (2017) |
title_fullStr | SEOM clinical guidelines for anaplastic gliomas (2017) |
title_full_unstemmed | SEOM clinical guidelines for anaplastic gliomas (2017) |
title_short | SEOM clinical guidelines for anaplastic gliomas (2017) |
title_sort | seom clinical guidelines for anaplastic gliomas (2017) |
topic | Clinical Guides in Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785606/ https://www.ncbi.nlm.nih.gov/pubmed/29058264 http://dx.doi.org/10.1007/s12094-017-1762-7 |
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