Distinct Gene Expression and Epigenetic Signatures in Hepatocyte-like Cells Produced by Different Strategies from the Same Donor

Hepatocyte-like cells (HLCs) can be generated through directed differentiation or transdifferentiation. Employing two strategies, we generated induced pluripotent stem cell (iPSC)-HLCs and hiHeps from the same donor cell line. Both types of HLCs clustered distinctly from each other during gene expre...

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Detalles Bibliográficos
Autores principales: Gao, Yimeng, Zhang, Xiaoran, Zhang, Ludi, Cen, Jin, Ni, Xuan, Liao, Xiaoying, Yang, Chenxi, Li, Ying, Chen, Xiaotao, Zhang, Zhao, Shu, Yajing, Cheng, Xin, Hay, David C., Lai, Dongmei, Pan, Guoyu, Wei, Gang, Hui, Lijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785700/
https://www.ncbi.nlm.nih.gov/pubmed/29173899
http://dx.doi.org/10.1016/j.stemcr.2017.10.019

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