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Generation of “Off-the-Shelf” Natural Killer Cells from Peripheral Blood Cell-Derived Induced Pluripotent Stem Cells

Current donor cell-dependent strategies can only produce limited “made-to-order” therapeutic natural killer (NK) cells for limited patients. To provide unlimited “off-the-shelf” NK cells that serve many recipients, we designed and demonstrated a holistic manufacturing scheme to mass-produce NK cells...

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Detalles Bibliográficos
Autores principales: Zeng, Jieming, Tang, Shin Yi, Toh, Lai Ling, Wang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785702/
https://www.ncbi.nlm.nih.gov/pubmed/29173894
http://dx.doi.org/10.1016/j.stemcr.2017.10.020