Cargando…

Neutrophils: driving progression and poor prognosis in hepatocellular carcinoma?

BACKGROUND: Irrespective of the underlying aetiology, 90% of hepatocellular carcinomas arise and progress on a background of chronic inflammation. We have explored the independent prognostic value of circulating inflammatory cells. METHODS: Peripheral blood count data sets from 583 consecutive patie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Margetts, Jane, Ogle, Laura F, Chan, Stephen L, Chan, Anthony W H, Chan, K C Allen, Jamieson, David, Willoughby, Catherine E, Mann, Derek A, Wilson, Caroline L, Manas, Derek M, Yeo, Winnie, Reeves, Helen L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785742/ https://www.ncbi.nlm.nih.gov/pubmed/29123264 http://dx.doi.org/10.1038/bjc.2017.386

Ejemplares similares

Elevated preoperative neutrophil/lymphocyte ratio is associated with poor prognosis in soft-tissue sarcoma patients
por: Szkandera, J, et al.
Publicado: (2013)

IGFBP7 is associated with poor prognosis in oesophageal adenocarcinoma and is regulated by promoter DNA methylation
por: Smith, E, et al.
Publicado: (2014)

SERPINB3 is associated with TGF-β1 and cytoplasmic β-catenin expression in hepatocellular carcinomas with poor prognosis
por: Turato, C, et al.
Publicado: (2014)

Low expression of the putative tumour suppressor spinophilin is associated with higher proliferative activity and poor prognosis in patients with hepatocellular carcinoma
por: Aigelsreiter, A, et al.
Publicado: (2013)

CD47 overexpression is associated with decreased neutrophil apoptosis/phagocytosis and poor prognosis in non-small-cell lung cancer patients
por: Barrera, Lourdes, et al.
Publicado: (2017)

Id-1 and Id-2 are markers for metastasis and prognosis in oesophageal squamous cell carcinoma
por: Yuen, H-F, et al.
Publicado: (2007)

Mutations in Rb1 pathway-related genes are associated with poor prognosis in Anaplastic Astrocytomas
por: Bäcklund, L M, et al.
Publicado: (2005)

Two-marker protein profile predicts poor prognosis in patients with early rectal cancer
por: Zlobec, I, et al.
Publicado: (2008)

Expression of AT1 and AT2 angiotensin receptors in astrocytomas is associated with poor prognosis
por: Arrieta, O, et al.
Publicado: (2008)

Spindle cell morphology is related to poor prognosis in vulvar squamous cell carcinoma
por: Trietsch, M D, et al.
Publicado: (2013)

PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer
por: Wigfield, S M, et al.
Publicado: (2008)

Arpin downregulation in breast cancer is associated with poor prognosis
por: Lomakina, Maria E, et al.
Publicado: (2016)

Increased neutrophil-lymphocyte ratio is a poor prognostic factor in patients with primary operable and inoperable pancreatic cancer
por: Stotz, M, et al.
Publicado: (2013)

Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome
por: Wightman, S C, et al.
Publicado: (2015)

Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis
por: Voorneveld, P W, et al.
Publicado: (2013)

Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localised and is associated with poor prognosis in colorectal cancer
por: Carpenter, B, et al.
Publicado: (2006)

Overexpression of TMPRSS4 in non-small cell lung cancer is associated with poor prognosis in patients with squamous histology
por: Larzabal, L, et al.
Publicado: (2011)

High expression of TROP2 correlates with poor prognosis in pancreatic cancer
por: Fong, D, et al.
Publicado: (2008)

Expression of N-acetylglucosaminyltransferase V in endometrial cancer correlates with poor prognosis
por: Yamamoto, E, et al.
Publicado: (2007)

Overexpression of podocalyxin-like protein is an independent factor of poor prognosis in colorectal cancer
por: Larsson, A, et al.
Publicado: (2011)

Serum amyloid A is elevated in the serum of lung cancer patients with poor prognosis
por: Cho, W C S, et al.
Publicado: (2010)

High level of interleukin-10 in serum predicts poor prognosis in multiple myeloma
por: Wang, Hua, et al.
Publicado: (2016)

High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer
por: Wang, E L, et al.
Publicado: (2010)

RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas
por: Deb, S, et al.
Publicado: (2014)

Overexpression of stathmin in oral squamous-cell carcinoma: correlation with tumour progression and poor prognosis
por: Kouzu, Y, et al.
Publicado: (2006)

Serum 20S proteasome is elevated in patients with renal cell carcinoma and associated with poor prognosis
por: de Martino, M, et al.
Publicado: (2012)

The elevated preoperative platelet-to-lymphocyte ratio predicts poor prognosis in breast cancer patients
por: Krenn-Pilko, S, et al.
Publicado: (2014)

Overexpression of glypican-1 implicates poor prognosis and their chemoresistance in oesophageal squamous cell carcinoma
por: Hara, Hisashi, et al.
Publicado: (2016)

Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers
por: Takahashi, Y, et al.
Publicado: (2014)

Biomarker-based prognosis in hepatocellular carcinoma: validation and extension of the BALAD model
por: Fox, R, et al.
Publicado: (2014)

Nuclear survivin expression is associated with HPV-independent carcinogenesis and is an indicator of poor prognosis in oropharyngeal cancer
por: Preuss, S F, et al.
Publicado: (2008)

A loss of c-kit expression is associated with an advanced stage and poor prognosis in breast cancer
por: Tsutsui, S, et al.
Publicado: (2006)

High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer
por: Hamano, R, et al.
Publicado: (2012)

Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer
por: Boman, K, et al.
Publicado: (2013)

Aurora kinase A (AURKA) expression in colorectal cancer liver metastasis is associated with poor prognosis
por: Goos, J A C M, et al.
Publicado: (2013)

Overexpression of nucleostemin contributes to an advanced malignant phenotype and a poor prognosis in oral squamous cell carcinoma
por: Yoshida, R, et al.
Publicado: (2014)

Serpin peptidase inhibitor clade A member 1 is a biomarker of poor prognosis in gastric cancer
por: Kwon, C H, et al.
Publicado: (2014)

Activation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinoma
por: Hagiwara, S, et al.
Publicado: (2012)

Expression of activated signal transducer and activator of transcription-3 predicts poor prognosis in cervical squamous-cell carcinoma
por: Takemoto, S, et al.
Publicado: (2009)

High leukocyte mitochondrial DNA content contributes to poor prognosis in glioma patients through its immunosuppressive effect
por: Chen, Y, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_h83q4vdmtvfpmgseknvqja3noe