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Highly selective inhibition of Bruton’s tyrosine kinase attenuates skin and brain disease in murine lupus
BACKGROUND: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects different end organs, including skin and brain. We and others have previously shown the importance of macrophages in the pathogenesis of cutaneous and neuropsychiatric lupus. Additionally, autoantibodies pro...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785891/ https://www.ncbi.nlm.nih.gov/pubmed/29370834 http://dx.doi.org/10.1186/s13075-017-1500-0 |