Highly selective inhibition of Bruton’s tyrosine kinase attenuates skin and brain disease in murine lupus

BACKGROUND: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects different end organs, including skin and brain. We and others have previously shown the importance of macrophages in the pathogenesis of cutaneous and neuropsychiatric lupus. Additionally, autoantibodies pro...

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Detalles Bibliográficos
Autores principales: Chalmers, Samantha A., Wen, Jing, Doerner, Jessica, Stock, Ariel, Cuda, Carla M., Makinde, Hadijat M., Perlman, Harris, Bosanac, Todd, Webb, Deborah, Nabozny, Gerald, Fine, Jay S., Klein, Elliott, Ramanujam, Meera, Putterman, Chaim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785891/
https://www.ncbi.nlm.nih.gov/pubmed/29370834
http://dx.doi.org/10.1186/s13075-017-1500-0

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