An xQTL map integrates the genetic architecture of the human brain’s transcriptome and epigenome

We report a novel multi-omic resource generated by applying quantitative trait locus (xQTL) analyses to RNA sequence, DNA methylation, and histone acetylation data from the dorsolateral prefrontal cortex of 411 older adult individuals that have all three data types. We identify SNPs significantly as...

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Detalles Bibliográficos
Autores principales: Ng, B, White, CC, Klein, H, Sieberts, SK, McCabe, C, Patrick, E, Xu, J, Yu, L, Gaiteri, C, Bennett, DA, Mostafavi, S, De Jager, PL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785926/
https://www.ncbi.nlm.nih.gov/pubmed/28869584
http://dx.doi.org/10.1038/nn.4632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785926/
https://www.ncbi.nlm.nih.gov/pubmed/28869584
http://dx.doi.org/10.1038/nn.4632

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